Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2720227..2720900 Replicon chromosome
Accession NZ_CP118687
Organism Rhizobium sp. MJ22

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PO862_RS13675 Protein ID WP_272782126.1
Coordinates 2720227..2720640 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PO862_RS13680 Protein ID WP_272782124.1
Coordinates 2720637..2720900 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO862_RS13665 (PO862_13665) 2717637..2718860 - 1224 WP_183608225.1 efflux RND transporter periplasmic adaptor subunit -
PO862_RS13670 (PO862_13670) 2719116..2720048 - 933 WP_273884229.1 adenylate/guanylate cyclase domain-containing protein -
PO862_RS13675 (PO862_13675) 2720227..2720640 - 414 WP_272782126.1 type II toxin-antitoxin system VapC family toxin Toxin
PO862_RS13680 (PO862_13680) 2720637..2720900 - 264 WP_272782124.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PO862_RS13685 (PO862_13685) 2721025..2722575 - 1551 WP_273884230.1 SpoVR family protein -
PO862_RS13690 (PO862_13690) 2722572..2723846 - 1275 WP_183608222.1 YeaH/YhbH family protein -
PO862_RS13695 (PO862_13695) 2723859..2725802 - 1944 WP_183608221.1 PrkA family serine protein kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(9-55)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15027.48 Da        Isoelectric Point: 6.7216

>T273373 WP_272782126.1 NZ_CP118687:c2720640-2720227 [Rhizobium sp. MJ22]
MTAWMLDTNIASHVIKGDRPEILKRLAALPMDEIVISSVTEGELLYGLAKRGYPKALSERVRQFLLRVDVLPWDHDVTRA
YGDLRAACEVKGVALAPLEMMIAAHAVATAATLVTRDKAFARVSEPLKLDGWANEGS

Download         Length: 414 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9952.93 Da        Isoelectric Point: 4.8553

>AT273373 WP_272782124.1 NZ_CP118687:c2720900-2720637 [Rhizobium sp. MJ22]
VASKTAKIFTTGRSQAVRLPADFRFEESEVFVRRDPKTGDVILSRKSDSWDGLFELHGRDQVPDDFMGPADRSQPSQDHD
PFEGWRE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References