Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 437382..437984 Replicon chromosome
Accession NZ_CP118687
Organism Rhizobium sp. MJ22

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PO862_RS02165 Protein ID WP_275034092.1
Coordinates 437739..437984 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PO862_RS02160 Protein ID WP_275034090.1
Coordinates 437382..437729 (-) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO862_RS02140 (PO862_02140) 432759..433814 - 1056 WP_275034085.1 dTDP-glucose 4,6-dehydratase -
PO862_RS02145 (PO862_02145) 433995..435056 + 1062 WP_273880136.1 GDP-mannose 4,6-dehydratase -
PO862_RS02150 (PO862_02150) 435057..436007 + 951 WP_273880137.1 GDP-L-fucose synthase -
PO862_RS02155 (PO862_02155) 436236..437258 + 1023 WP_275034088.1 class I SAM-dependent methyltransferase -
PO862_RS02160 (PO862_02160) 437382..437729 - 348 WP_275034090.1 helix-turn-helix transcriptional regulator Antitoxin
PO862_RS02165 (PO862_02165) 437739..437984 - 246 WP_275034092.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PO862_RS02175 (PO862_02175) 438503..440065 + 1563 WP_273883494.1 exopolyphosphatase -
PO862_RS02180 (PO862_02180) 440074..440793 + 720 WP_272782982.1 RlmE family RNA methyltransferase -
PO862_RS02185 (PO862_02185) 440949..441332 + 384 WP_275035628.1 VOC family protein -
PO862_RS02190 (PO862_02190) 441387..442811 - 1425 WP_183605789.1 DHA2 family efflux MFS transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gmd 432759..452440 19681


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(63-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9033.57 Da        Isoelectric Point: 10.4109

>T273372 WP_275034092.1 NZ_CP118687:c437984-437739 [Rhizobium sp. MJ22]
MKEIAYSKAAAKALRKMQPKRAAAIVAKVEAFANSEPVDLKKLQGSEFFRIRVGQDRVIIDDQTMQVLVIKAGPRGDIYN
E

Download         Length: 246 bp

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12619.31 Da        Isoelectric Point: 4.2700

>AT273372 WP_275034090.1 NZ_CP118687:c437729-437382 [Rhizobium sp. MJ22]
MGEIQTLTIDGKGYVLLSEEDYCDLVDLSEARAAKARIDAGEETWPEDVVKALISGEDPVRVFRKHRGMSVKELAEKAGL
SQPYLSEIETGKKEGSLDALKAIARILDVDLDDLV

Download         Length: 348 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References