Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 22512..23182 Replicon plasmid pKNA09
Accession NZ_CP118672
Organism Komagataeibacter nataicola strain DS12

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LV564_RS00145 Protein ID WP_275881073.1
Coordinates 22760..23182 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LV564_RS00140 Protein ID WP_275879433.1
Coordinates 22512..22763 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LV564_RS00120 (LV564_00120) 18535..20184 + 1650 WP_275881094.1 2-oxoglutarate and iron-dependent oxygenase domain-containing protein -
LV564_RS00125 (LV564_00125) 20529..20693 - 165 WP_166498087.1 hypothetical protein -
LV564_RS00130 (LV564_00130) 21003..21488 - 486 WP_275881072.1 hypothetical protein -
LV564_RS00135 (LV564_00135) 21887..22309 + 423 WP_034933799.1 hypothetical protein -
LV564_RS00140 (LV564_00140) 22512..22763 + 252 WP_275879433.1 plasmid stabilization protein Antitoxin
LV564_RS00145 (LV564_00145) 22760..23182 + 423 WP_275881073.1 type II toxin-antitoxin system VapC family toxin Toxin
LV564_RS00150 (LV564_00150) 23388..24119 - 732 WP_275881074.1 SprT family zinc-dependent metalloprotease -
LV564_RS00155 (LV564_00155) 24119..27418 - 3300 WP_275881075.1 HsdR family type I site-specific deoxyribonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..38109 38109


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15176.44 Da        Isoelectric Point: 4.4569

>T273364 WP_275881073.1 NZ_CP118672:22760-23182 [Komagataeibacter nataicola]
MILLDTNVISEPWKPVPEPCVLAWIDAQAIETLFLSAVTVAELRFGIGAMPAGRRQTVLQERLEQDVLPLFEGRILSFDL
GASQAYAELMVRARCEGRAIGKADGYIAATAASRGYAVASRDVSPFEAAGVRVLNPWEDA

Download         Length: 423 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9088.34 Da        Isoelectric Point: 6.4658

>AT273364 WP_275879433.1 NZ_CP118672:22512-22763 [Komagataeibacter nataicola]
MSSVVIRNLPEETHRALKAQAVLHGRSTEAEIRTILEAAVRPQQRVRLGSLLAAIGREAGVSEQDVTALQVRDQTPAEPM
SFE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References