Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1(toxin) |
Location | 4662574..4663190 | Replicon | chromosome |
Accession | NZ_CP118633 | ||
Organism | Salmonella enterica subsp. enterica serovar Anatum strain 2089b |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | PWO88_RS22705 | Protein ID | WP_023243564.1 |
Coordinates | 4662574..4662948 (-) | Length | 125 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | A0A8E9YHE9 |
Locus tag | PWO88_RS22710 | Protein ID | WP_001523745.1 |
Coordinates | 4662948..4663190 (-) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PWO88_RS22690 (4660076) | 4660076..4660978 | + | 903 | WP_000331364.1 | formate dehydrogenase subunit beta | - |
PWO88_RS22695 (4660975) | 4660975..4661610 | + | 636 | WP_000829025.1 | formate dehydrogenase cytochrome b556 subunit | - |
PWO88_RS22700 (4661607) | 4661607..4662536 | + | 930 | WP_000027730.1 | formate dehydrogenase accessory protein FdhE | - |
PWO88_RS22705 (4662574) | 4662574..4662948 | - | 375 | WP_023243564.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
PWO88_RS22710 (4662948) | 4662948..4663190 | - | 243 | WP_001523745.1 | CopG family transcriptional regulator | Antitoxin |
PWO88_RS22715 (4663395) | 4663395..4664324 | + | 930 | WP_001162860.1 | alpha/beta hydrolase | - |
PWO88_RS22720 (4664410) | 4664410..4664721 | + | 312 | WP_000558166.1 | type II toxin-antitoxin system HigB family toxin | - |
PWO88_RS22725 (4664718) | 4664718..4665164 | + | 447 | WP_031609809.1 | type II toxin-antitoxin system HigA family antitoxin | - |
PWO88_RS22730 (4665179) | 4665179..4666120 | - | 942 | WP_001518251.1 | fatty acid biosynthesis protein FabY | - |
PWO88_RS22735 (4666165) | 4666165..4666602 | - | 438 | WP_000560969.1 | D-aminoacyl-tRNA deacylase | - |
PWO88_RS22740 (4666599) | 4666599..4667471 | - | 873 | WP_000921423.1 | virulence factor BrkB family protein | - |
PWO88_RS22745 (4667465) | 4667465..4668064 | - | 600 | WP_000965695.1 | glucose-1-phosphatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 125 a.a. Molecular weight: 13880.13 Da Isoelectric Point: 7.3567
>T273348 WP_023243564.1 NZ_CP118633:c4662948-4662574 [Salmonella enterica subsp. enterica serovar Anatum]
MVKGSALFDTNILIDLFSGRIEAKHALEAYPPQNAISLITWMEVMAGAKKYHQENRTRIALSAFNIIGVTQEIAERSVIV
RQEYGMKLPDAIILATAQVHRCELVTRNTKDFADIPGVITPYHL
MVKGSALFDTNILIDLFSGRIEAKHALEAYPPQNAISLITWMEVMAGAKKYHQENRTRIALSAFNIIGVTQEIAERSVIV
RQEYGMKLPDAIILATAQVHRCELVTRNTKDFADIPGVITPYHL
Download Length: 375 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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