Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 854915..855575 Replicon chromosome
Accession NZ_CP118633
Organism Salmonella enterica subsp. enterica serovar Anatum strain 2089b

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag PWO88_RS04115 Protein ID WP_000244756.1
Coordinates 855162..855575 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag PWO88_RS04110 Protein ID WP_000351186.1
Coordinates 854915..855181 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWO88_RS04090 (850844) 850844..852277 - 1434 WP_001230140.1 6-phospho-beta-glucosidase BglA -
PWO88_RS04095 (852435) 852435..852746 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
PWO88_RS04100 (852910) 852910..853569 + 660 WP_000250289.1 hemolysin III family protein -
PWO88_RS04105 (853685) 853685..854665 - 981 WP_000874178.1 tRNA-modifying protein YgfZ -
PWO88_RS04110 (854915) 854915..855181 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
PWO88_RS04115 (855162) 855162..855575 + 414 WP_000244756.1 protein YgfX Toxin
PWO88_RS04120 (855628) 855628..856149 - 522 WP_001055885.1 flavodoxin FldB -
PWO88_RS04125 (856262) 856262..857158 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
PWO88_RS04130 (857182) 857182..857895 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PWO88_RS04135 (857901) 857901..859634 + 1734 WP_000813389.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T273333 WP_000244756.1 NZ_CP118633:855162-855575 [Salmonella enterica subsp. enterica serovar Anatum]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT273333 WP_000351186.1 NZ_CP118633:854915-855181 [Salmonella enterica subsp. enterica serovar Anatum]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References