Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 621962..622539 Replicon plasmid pVWJL.P1
Accession NZ_CP118630
Organism Pantoea dispersa strain VWJL.P1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PWF83_RS22335 Protein ID WP_058770345.1
Coordinates 622207..622539 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID A0A8E1V6C0
Locus tag PWF83_RS22330 Protein ID WP_058770344.1
Coordinates 621962..622207 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWF83_RS22310 (PWF83_22320) 617324..618277 + 954 WP_127835008.1 carbohydrate kinase family protein -
PWF83_RS22315 (PWF83_22325) 618281..619363 + 1083 WP_275029538.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
PWF83_RS22320 (PWF83_22330) 619483..620892 - 1410 WP_058781049.1 MFS transporter -
PWF83_RS22325 (PWF83_22335) 621008..621862 + 855 WP_058770343.1 helix-turn-helix transcriptional regulator -
PWF83_RS22330 (PWF83_22340) 621962..622207 + 246 WP_058770344.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PWF83_RS22335 (PWF83_22345) 622207..622539 + 333 WP_058770345.1 endoribonuclease MazF Toxin
PWF83_RS22340 (PWF83_22350) 622645..622818 + 174 WP_021508895.1 hypothetical protein -
PWF83_RS22345 (PWF83_22355) 622848..623195 + 348 WP_021508894.1 hypothetical protein -
PWF83_RS22350 (PWF83_22360) 623235..624428 - 1194 WP_058781047.1 zinc-dependent alcohol dehydrogenase -
PWF83_RS22355 (PWF83_22365) 624692..625399 + 708 WP_021508892.1 phage antirepressor KilAC domain-containing protein -
PWF83_RS22360 (PWF83_22370) 625434..625649 - 216 WP_021508891.1 hypothetical protein -
PWF83_RS22365 (PWF83_22375) 625791..626972 - 1182 WP_125310195.1 FAD-binding oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..708540 708540


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-107)

Antitoxin

SpoVT-AbrB domain

(7-49)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12009.84 Da        Isoelectric Point: 7.8855

>T273329 WP_058770345.1 NZ_CP118630:622207-622539 [Pantoea dispersa]
MVSRFVPDAGDLIWLDFDPTLGHEQGGHRPAVVLSPFAYNNKVGMLLCVPCTTQVKGYPFEVSLTGSRDSVALADQVTSI
DWRARKVVKKSHVTAEELSEIRAKAKALIG

Download         Length: 333 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8955.25 Da        Isoelectric Point: 4.5580

>AT273329 WP_058770344.1 NZ_CP118630:621962-622207 [Pantoea dispersa]
MTTVTLKKWGNSPSIRIPSSVMQSASLSVDDKLELSVEDGKLILVPLREKVYSLDALLDEITDDNVHDKIDFGPSVGKER
I

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References