273325

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 4162987..4164554 Replicon chromosome
Accession NZ_CP118629
Organism Pantoea dispersa strain VWJL.P1

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag PWF83_RS19480 Protein ID WP_275027297.1
Coordinates 4162987..4164297 (-) Length 437 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag PWF83_RS19485 Protein ID WP_104189496.1
Coordinates 4164297..4164554 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWF83_RS19455 (PWF83_19465) 4158483..4159145 - 663 WP_058758205.1 6-phosphogluconate phosphatase -
PWF83_RS19460 (PWF83_19470) 4159297..4160610 + 1314 WP_058770726.1 NCS2 family permease -
PWF83_RS19465 (PWF83_19475) 4160638..4161402 - 765 WP_125310371.1 phosphopantetheinyl transferase -
PWF83_RS19470 (PWF83_19480) 4161696..4162205 + 510 WP_031279601.1 flavin reductase family protein -
PWF83_RS19475 (PWF83_19485) 4162247..4162837 - 591 WP_021506918.1 malonic semialdehyde reductase -
PWF83_RS19480 (PWF83_19490) 4162987..4164297 - 1311 WP_275027297.1 type II toxin-antitoxin system HipA family toxin Toxin
PWF83_RS19485 (PWF83_19495) 4164297..4164554 - 258 WP_104189496.1 helix-turn-helix domain-containing protein Antitoxin
PWF83_RS19490 (PWF83_19500) 4164762..4166126 - 1365 WP_021506917.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
PWF83_RS19495 (PWF83_19505) 4166207..4167853 - 1647 WP_021506916.1 membrane protein insertase YidC -
PWF83_RS19500 (PWF83_19510) 4167856..4168113 - 258 WP_275027302.1 membrane protein insertion efficiency factor YidD -
PWF83_RS19505 (PWF83_19515) 4168077..4168436 - 360 WP_040679622.1 ribonuclease P protein component -
PWF83_RS19510 (PWF83_19520) 4168452..4168592 - 141 WP_000831330.1 50S ribosomal protein L34 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-65)


Sequences

Toxin        


Download         Length: 437 a.a.        Molecular weight: 49084.20 Da        Isoelectric Point: 8.1524

>T273325 WP_275027297.1 NZ_CP118629:c4164297-4162987 [Pantoea dispersa]
MTELDVYMNGYRTGVFSRAATGAHTFRYYESWLNQPGSRPISLSMPLRHQPYKGAEVYNFFDNLLPDNPEIRARILSRYQ
ASSTQPFDLLAKVGSDTIGALQLLPPDSKPHTVRTIDYRRLSDSELEKILSGYQSGAPLGMLEELTDFRISLAGAQEKTA
LLRIDQQWCLPQGNTPTTHILKLPIGNIQSHSHRIDLSDSVENEWLCTLIAREFGLAVPPCFIVNTGKIKALAVERFDRR
YASDGQWIMRLPQEDFCQVLNVPAAGKYESHGGPGISAIMDYLLNSVNVEQDRYDFMKAQVLFWLLAATDGHAKNFSIFI
EAEGRFRLTPFYDILSIYPVIGGAGLHIRDAKLAMGLNGSKDRKAAIEHIFPRHFIETAKTTKFALTAMAHILDEFRART
PEVIQRVQEQIPAAFPLRVSQTILNGFKARAARLQQ

Download         Length: 1311 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9677.11 Da        Isoelectric Point: 8.5776

>AT273325 WP_104189496.1 NZ_CP118629:c4164554-4164297 [Pantoea dispersa]
MKITSAKQLSSYLKDRRLTEALSQAKVASKIGIRQDTVSSFELQPETTRLDTLFRILAALDLEMEIKPRGLPSAKQDPDG
WKEEW

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References