Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3665311..3666215 Replicon chromosome
Accession NZ_CP118629
Organism Pantoea dispersa strain VWJL.P1

Toxin (Protein)


Gene name - Uniprot ID A0A8E1V7L7
Locus tag PWF83_RS17125 Protein ID WP_058774932.1
Coordinates 3665751..3666215 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A246NMT1
Locus tag PWF83_RS17120 Protein ID WP_058757556.1
Coordinates 3665311..3665754 (+) Length 148 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWF83_RS17100 (PWF83_17110) 3661423..3661818 + 396 WP_031279757.1 transposase -
PWF83_RS17105 (PWF83_17115) 3662727..3663680 - 954 WP_275026703.1 DMT family transporter -
PWF83_RS17110 (PWF83_17120) 3663753..3664583 - 831 WP_132465743.1 AraC family transcriptional regulator -
PWF83_RS17115 (PWF83_17125) 3664710..3665237 + 528 WP_275026707.1 isochorismatase family protein -
PWF83_RS17120 (PWF83_17130) 3665311..3665754 + 444 WP_058757556.1 DUF2384 domain-containing protein Antitoxin
PWF83_RS17125 (PWF83_17135) 3665751..3666215 + 465 WP_058774932.1 RES domain-containing protein Toxin
PWF83_RS17130 (PWF83_17140) 3666267..3666809 - 543 WP_021507842.1 single-stranded DNA-binding protein SSB1 -
PWF83_RS17135 (PWF83_17145) 3667031..3669859 + 2829 WP_021507843.1 excinuclease ABC subunit UvrA -
PWF83_RS17140 (PWF83_17150) 3670135..3671199 + 1065 WP_275026712.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-147)

Antitoxin

(15-147)


Sequences


Toxin        


Download         Length: 155 a.a.        Molecular weight: 17117.59 Da        Isoelectric Point: 5.1259

>T273323 WP_058774932.1 NZ_CP118629:3665751-3666215 [Pantoea dispersa]
VIFYRLTKSQYAAEAWSGYGAKQYGGRWNHKGYPTVYVATSVSLAALEVLVHIGRESVLDEYTLFSIDIPDAEVAYLAEA
FLPPDWRHDPAPLSTMDLGTGWLQSAEGAALMLPSTIIPMENNAILNPLHPAFSDYLPGVKALPFMFDRRLIRT

Download         Length: 465 bp


Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16114.59 Da        Isoelectric Point: 9.9132

>AT273323 WP_058757556.1 NZ_CP118629:3665311-3665754 [Pantoea dispersa]
MRAYIPQPGANDNALWRVAGLPPRGIELTRMLEAGLPVAVIDDIRHWSAMTRAEIMKVTGINERNIARRKSTGKSLSPDE
SERVARFVRVMDAAVQLFAGNKEEATQWLSRPVKGLGNVAPITLLTTESGALDVLDLIGRLEHGVFS

Download         Length: 444 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A246NMT1

References