Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 6341541..6342061 Replicon chromosome
Accession NZ_CP118614
Organism Nocardiopsis sp. DZFXJ 01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PV789_RS27735 Protein ID WP_274975260.1
Coordinates 6341541..6341798 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PV789_RS27740 Protein ID WP_274975261.1
Coordinates 6341795..6342061 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PV789_RS27710 (PV789_27710) 6336850..6337653 + 804 WP_274975256.1 ABC transporter ATP-binding protein -
PV789_RS27715 (PV789_27715) 6337668..6338513 + 846 WP_274975257.1 ABC transporter permease -
PV789_RS27720 (PV789_27720) 6338523..6339632 + 1110 WP_274975258.1 ABC transporter substrate-binding protein -
PV789_RS27725 (PV789_27725) 6339775..6340869 + 1095 WP_274975259.1 LLM class flavin-dependent oxidoreductase -
PV789_RS27730 (PV789_27730) 6341140..6341475 + 336 WP_248772574.1 DUF2795 domain-containing protein -
PV789_RS27735 (PV789_27735) 6341541..6341798 - 258 WP_274975260.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PV789_RS27740 (PV789_27740) 6341795..6342061 - 267 WP_274975261.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PV789_RS27745 (PV789_27745) 6342175..6343671 + 1497 WP_274975262.1 PucR family transcriptional regulator -
PV789_RS27750 (PV789_27750) 6344016..6345332 + 1317 WP_274975263.1 MFS transporter -
PV789_RS27755 (PV789_27755) 6345553..6346821 + 1269 WP_274975264.1 Na+/H+ antiporter NhaA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-64)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9762.24 Da        Isoelectric Point: 9.5565

>T273314 WP_274975260.1 NZ_CP118614:c6341798-6341541 [Nocardiopsis sp. DZFXJ 01]
VSYRTVFRPEAGAELRKLPRNVAMNVFRKLTELETDPLGFGTTALVGDPEVRRLRVGDYRMIYTVEESRLVVWVVHIGHR
SGVYD

Download         Length: 258 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10320.77 Da        Isoelectric Point: 4.4152

>AT273314 WP_274975261.1 NZ_CP118614:c6342061-6341795 [Nocardiopsis sp. DZFXJ 01]
MSEMQVESIRQVRDHIADVVDRADREDSPTVITRRGKEVAAVVPIDLLRRYQRFEEQEILRMVRERMDNPEPGIPMEQVM
AEIMEGPE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References