273312

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1743575..1744055 Replicon chromosome
Accession NZ_CP118614
Organism Nocardiopsis sp. DZFXJ 01

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag PV789_RS07765 Protein ID WP_274976787.1
Coordinates 1743783..1744055 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag PV789_RS07760 Protein ID WP_274976786.1
Coordinates 1743575..1743799 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PV789_RS07735 (PV789_07735) 1739010..1739807 + 798 WP_274976781.1 TIM barrel protein -
PV789_RS07740 (PV789_07740) 1739890..1740780 + 891 WP_274976782.1 2-hydroxy-3-oxopropionate reductase -
PV789_RS07745 (PV789_07745) 1740991..1742706 + 1716 WP_274976783.1 glyoxylate carboligase -
PV789_RS07750 (PV789_07750) 1742934..1743284 + 351 WP_274976784.1 hypothetical protein -
PV789_RS07755 (PV789_07755) 1743337..1743501 - 165 WP_274976785.1 type II toxin-antitoxin system VapB family antitoxin -
PV789_RS07760 (PV789_07760) 1743575..1743799 + 225 WP_274976786.1 TraY domain-containing protein Antitoxin
PV789_RS07765 (PV789_07765) 1743783..1744055 + 273 WP_274976787.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PV789_RS07770 (PV789_07770) 1744207..1745268 + 1062 WP_274976788.1 alkene reductase -
PV789_RS07775 (PV789_07775) 1745711..1747411 + 1701 WP_274976789.1 2-isopropylmalate synthase -
PV789_RS07780 (PV789_07780) 1747478..1748188 - 711 WP_274976790.1 DUF2625 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10635.32 Da        Isoelectric Point: 10.0371

>T273312 WP_274976787.1 NZ_CP118614:1743783-1744055 [Nocardiopsis sp. DZFXJ 01]
MTWKVELHDDARRDLRKLDPQVVRRILRFLKDRVEGADDPRCLGEALKGSRLGDLWRYRVGDYRVVVDIRDGLLVVLVVH
IAHRSQVYRD

Download         Length: 273 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8399.41 Da        Isoelectric Point: 4.3633

>AT273312 WP_274976786.1 NZ_CP118614:1743575-1743799 [Nocardiopsis sp. DZFXJ 01]
MLALRLPAEIEDRLEALAKETGRSKSFYAREAIVAHLDELEEVYLAERRLEDLRAGRSGTTPLSEVMDEHDVES

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References