Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 600924..601563 Replicon chromosome
Accession NZ_CP118614
Organism Nocardiopsis sp. DZFXJ 01

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PV789_RS02820 Protein ID WP_248773323.1
Coordinates 600924..601343 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PV789_RS02825 Protein ID WP_212641706.1
Coordinates 601348..601563 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PV789_RS02805 (PV789_02805) 596458..597327 + 870 WP_274976031.1 pantoate--beta-alanine ligase -
PV789_RS02810 (PV789_02810) 597435..600026 + 2592 WP_274976032.1 L-aspartate oxidase -
PV789_RS02815 (PV789_02815) 600091..600873 + 783 WP_274976033.1 type III pantothenate kinase -
PV789_RS02820 (PV789_02820) 600924..601343 - 420 WP_248773323.1 PIN domain nuclease Toxin
PV789_RS02825 (PV789_02825) 601348..601563 - 216 WP_212641706.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PV789_RS02830 (PV789_02830) 601669..602625 - 957 WP_274976034.1 cation diffusion facilitator family transporter -
PV789_RS02835 (PV789_02835) 602722..604326 + 1605 WP_274978030.1 bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX -
PV789_RS02840 (PV789_02840) 605029..605352 + 324 WP_212641704.1 LuxR C-terminal-related transcriptional regulator -
PV789_RS02845 (PV789_02845) 605485..606129 + 645 WP_274976035.1 amino-acid N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(2-35)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15885.11 Da        Isoelectric Point: 6.9594

>T273309 WP_248773323.1 NZ_CP118614:c601343-600924 [Nocardiopsis sp. DZFXJ 01]
VTKTYLLDTSAWLEYLGGTGSETHLFVRQLRDNRENVATTDPVICELLSGAKTEKAFFQLDAMLQAQTRLTVEPTFDFRE
SAMLYRGARSKGKTIRKHMDCLIAAVALRTDAVLVHCDRDFDHLAEVFPRLRVQRHDQD

Download         Length: 420 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8232.12 Da        Isoelectric Point: 4.1653

>AT273309 WP_212641706.1 NZ_CP118614:c601563-601348 [Nocardiopsis sp. DZFXJ 01]
MSRTNIDIDDELVTTVMEKYGLRTKREAVDFGLRHVAGSGDRYEMMLELEGSDVWEGDLDEMRRSGFEDEK

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References