Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 374873..375504 Replicon chromosome
Accession NZ_CP118614
Organism Nocardiopsis sp. DZFXJ 01

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PV789_RS01805 Protein ID WP_274975872.1
Coordinates 375103..375504 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PV789_RS01800 Protein ID WP_274975871.1
Coordinates 374873..375103 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PV789_RS01785 (PV789_01785) 371861..372502 - 642 WP_274975868.1 DUF1449 family protein -
PV789_RS01790 (PV789_01790) 372881..373321 + 441 WP_274975869.1 YciI family protein -
PV789_RS01795 (PV789_01795) 373476..374738 + 1263 WP_274975870.1 RNA polymerase sigma factor -
PV789_RS01800 (PV789_01800) 374873..375103 + 231 WP_274975871.1 hypothetical protein Antitoxin
PV789_RS01805 (PV789_01805) 375103..375504 + 402 WP_274975872.1 PIN domain-containing protein Toxin
PV789_RS01810 (PV789_01810) 375605..376591 + 987 WP_274975873.1 NAD-dependent epimerase/dehydratase family protein -
PV789_RS01815 (PV789_01815) 376672..376935 + 264 WP_274975874.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
PV789_RS01820 (PV789_01820) 377105..379720 - 2616 WP_274975875.1 ATP-dependent chaperone ClpB -
PV789_RS01825 (PV789_01825) 379807..380292 - 486 WP_248773132.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 353691..380292 26601


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14491.50 Da        Isoelectric Point: 5.1190

>T273308 WP_274975872.1 NZ_CP118614:375103-375504 [Nocardiopsis sp. DZFXJ 01]
MAVLLDANVLIALVVDDHVHHRAAEAWITEVDTAFATCPITQGSLVRLLLREGQDAEIARRVVAALAADERHEFWPDSIA
YTDVIMHGVIGHRQVTDAYLAQLARVHDGRLATFDQGLAKLHGDVAELVPTPG

Download         Length: 402 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8283.25 Da        Isoelectric Point: 4.7005

>AT273308 WP_274975871.1 NZ_CP118614:374873-375103 [Nocardiopsis sp. DZFXJ 01]
MRTTIDIPADLHQQAVSIARDTSRSLSETVTDLMRRGLGQSGPVREVSQSPRTGLPLVHLGSVITTEDVRALEDED

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References