Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 353470..354092 Replicon chromosome
Accession NZ_CP118614
Organism Nocardiopsis sp. DZFXJ 01

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PV789_RS01710 Protein ID WP_274978016.1
Coordinates 353688..354092 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PV789_RS01705 Protein ID WP_017563380.1
Coordinates 353470..353691 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PV789_RS01685 (PV789_01685) 349184..350470 + 1287 WP_274975852.1 MFS transporter -
PV789_RS01690 (PV789_01690) 350776..351240 + 465 WP_274975853.1 TIGR03668 family PPOX class F420-dependent oxidoreductase -
PV789_RS01695 (PV789_01695) 351470..352303 - 834 WP_274975854.1 SDR family oxidoreductase -
PV789_RS01700 (PV789_01700) 352520..353314 + 795 WP_274975855.1 GNAT family N-acetyltransferase -
PV789_RS01705 (PV789_01705) 353470..353691 + 222 WP_017563380.1 ribbon-helix-helix protein, CopG family Antitoxin
PV789_RS01710 (PV789_01710) 353688..354092 + 405 WP_274978016.1 PIN domain nuclease Toxin
PV789_RS01715 (PV789_01715) 354172..355989 - 1818 WP_274975856.1 acyl-CoA dehydrogenase -
PV789_RS01720 (PV789_01720) 356228..356731 - 504 WP_274975857.1 ATP-binding protein -
PV789_RS01725 (PV789_01725) 357133..357501 - 369 Protein_333 hypothetical protein -
PV789_RS01730 (PV789_01730) 357853..358050 - 198 WP_274975858.1 DUF397 domain-containing protein -
PV789_RS01735 (PV789_01735) 358095..358907 - 813 WP_274975859.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-121)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-37)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14791.22 Da        Isoelectric Point: 5.2252

>T273307 WP_274978016.1 NZ_CP118614:353688-354092 [Nocardiopsis sp. DZFXJ 01]
MMWLIDKSAFVRLAASPDAQEWATRIERGMVRISTVTRLEVGFSARTGGELRNFLGRPPLAVMPVEYVTPAMEDRAVEVQ
AMLADRGQHRAPGIPDLLIAAVAELAGLTLLHLDKDFELIAEITGQPVERLRTV

Download         Length: 405 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8175.12 Da        Isoelectric Point: 4.4550

>AT273307 WP_017563380.1 NZ_CP118614:353470-353691 [Nocardiopsis sp. DZFXJ 01]
MADVLIRNVPEDVLEVIDADARRQGLSRSEYLRRSLERTAHASGGAVTVDDLARFSEAFSDLADPEVMKRAWE

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References