Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 358802..359358 Replicon plasmid pCTYH.Ch1_2
Accession NZ_CP118612
Organism Ensifer adhaerens strain CTYH.Ch1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PWG15_RS34575 Protein ID WP_275027361.1
Coordinates 359068..359358 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PWG15_RS34570 Protein ID WP_275027360.1
Coordinates 358802..359080 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWG15_RS34550 (PWG15_34545) 354384..355223 + 840 WP_275027354.1 helix-turn-helix transcriptional regulator -
PWG15_RS34555 (PWG15_34550) 355228..356607 - 1380 WP_275027356.1 aspartate ammonia-lyase -
PWG15_RS34560 (PWG15_34555) 356604..357593 - 990 WP_275027358.1 asparaginase domain-containing protein -
PWG15_RS34565 (PWG15_34560) 357590..358351 - 762 WP_275027359.1 aspartate/glutamate racemase family protein -
PWG15_RS34570 (PWG15_34565) 358802..359080 + 279 WP_275027360.1 CopG family ribbon-helix-helix protein Antitoxin
PWG15_RS34575 (PWG15_34570) 359068..359358 + 291 WP_275027361.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PWG15_RS34580 (PWG15_34575) 360121..361137 - 1017 WP_275027362.1 LacI family DNA-binding transcriptional regulator -
PWG15_RS34585 (PWG15_34580) 361275..362309 + 1035 WP_275027363.1 Gfo/Idh/MocA family oxidoreductase -
PWG15_RS34590 (PWG15_34585) 362320..363222 + 903 WP_275027364.1 sugar phosphate isomerase/epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB 1..623840 623840


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10861.62 Da        Isoelectric Point: 9.9477

>T273305 WP_275027361.1 NZ_CP118612:359068-359358 [Ensifer adhaerens]
MPQIVFSPAAVRDLERLRKFLQPKSPLAAKRAAEAILKGVQALGAHPKMGRLIDDLPDQYREWLIDFGDSGYITRYRIDE
GVLTILAVRHQKESGF

Download         Length: 291 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10680.82 Da        Isoelectric Point: 4.9565

>AT273305 WP_275027360.1 NZ_CP118612:358802-359080 [Ensifer adhaerens]
MASPTSLKLDDELKGRVQHLAEIRRRSSHWIMREAIAQYVEREEKREALRQDTLDAWEEYQSTGLHATAAEVEKWLTTWG
TDDESGAPECHK

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References