Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES(toxin)
Location 1986367..1987244 Replicon plasmid pCTYH.Ch1_1
Accession NZ_CP118611
Organism Ensifer adhaerens strain CTYH.Ch1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PWG15_RS29175 Protein ID WP_275025010.1
Coordinates 1986367..1986873 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PWG15_RS29180 Protein ID WP_275027251.1
Coordinates 1986873..1987244 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWG15_RS29155 (PWG15_29150) 1981754..1982620 + 867 WP_275025005.1 sulfate ABC transporter permease subunit CysT -
PWG15_RS29160 (PWG15_29155) 1982610..1983566 + 957 WP_275025006.1 sulfate ABC transporter permease subunit CysW -
PWG15_RS29165 (PWG15_29160) 1983637..1984776 + 1140 WP_275025008.1 sulfate/molybdate ABC transporter ATP-binding protein -
PWG15_RS29170 (PWG15_29165) 1984952..1986316 + 1365 WP_275025009.1 FAD-binding oxidoreductase -
PWG15_RS29175 (PWG15_29170) 1986367..1986873 - 507 WP_275025010.1 RES domain-containing protein Toxin
PWG15_RS29180 (PWG15_29175) 1986873..1987244 - 372 WP_275027251.1 DUF2384 domain-containing protein Antitoxin
PWG15_RS29185 (PWG15_29180) 1987317..1988102 - 786 WP_275025011.1 crotonase/enoyl-CoA hydratase family protein -
PWG15_RS29190 (PWG15_29185) 1988099..1988968 - 870 WP_275025013.1 hydroxymethylglutaryl-CoA lyase -
PWG15_RS29195 (PWG15_29190) 1988965..1990953 - 1989 WP_275025014.1 acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha -
PWG15_RS29200 (PWG15_29195) 1990968..1991351 - 384 WP_275025015.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - wcbK / katA 1..2779603 2779603


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(8-161)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18627.06 Da        Isoelectric Point: 5.2200

>T273304 WP_275025010.1 NZ_CP118611:c1986873-1986367 [Ensifer adhaerens]
MSADEPVRLWRAYVPRWAHAPLSGDGAARFGGRWNPLGMPTIYATRELSTAWAEYNQGFVQHPALIAQLELRFARLAELT
AADGLAAFGLTKDIHRCEWRDALDHSLVPETHRLQAELDAGFDGLVYPSFMSPGGTCVALWRWNTGEGAELKVIDPDGRL
PETPASWL

Download         Length: 507 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 12902.84 Da        Isoelectric Point: 9.4389

>AT273304 WP_275027251.1 NZ_CP118611:c1987244-1986873 [Ensifer adhaerens]
MVAVGFNVSAAHYGESHSSFLSARLVADRLGVTLAELAKLIGVARNTLTAKSGARKVDAALSSVVRILAMAGEMAGDDGR
AVIWFKHQPIPGWAGKTAYDLVGEGKDDKVLAYLEAVRSGVYA

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References