273301

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 5197557..5198206 Replicon chromosome
Accession NZ_CP118607
Organism Pseudomonas sp. PSKL.D1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PVV54_RS23250 Protein ID WP_274907473.1
Coordinates 5197787..5198206 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PVV54_RS23245 Protein ID WP_274907472.1
Coordinates 5197557..5197787 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVV54_RS23225 (PVV54_23225) 5193021..5194349 - 1329 WP_274907469.1 precorrin-3B synthase -
PVV54_RS23230 (PVV54_23230) 5194451..5195662 + 1212 WP_274910489.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
PVV54_RS23235 (PVV54_23235) 5195655..5196749 + 1095 WP_274907470.1 cobalt-precorrin-5B (C(1))-methyltransferase -
PVV54_RS23240 (PVV54_23240) 5196746..5197462 + 717 WP_274907471.1 cobalt-precorrin-6A reductase -
PVV54_RS23245 (PVV54_23245) 5197557..5197787 + 231 WP_274907472.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PVV54_RS23250 (PVV54_23250) 5197787..5198206 + 420 WP_274907473.1 tRNA(fMet)-specific endonuclease VapC Toxin
PVV54_RS23255 (PVV54_23255) 5198326..5198763 + 438 WP_274907474.1 NfeD family protein -
PVV54_RS23260 (PVV54_23260) 5198789..5199643 + 855 WP_274907475.1 SPFH domain-containing protein -
PVV54_RS23265 (PVV54_23265) 5199753..5200142 + 390 WP_274907476.1 DUF2946 domain-containing protein -
PVV54_RS23270 (PVV54_23270) 5200191..5200676 + 486 WP_274907477.1 copper chaperone PCu(A)C -
PVV54_RS23275 (PVV54_23275) 5200702..5201127 + 426 WP_274907478.1 DUF2946 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-53)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15538.79 Da        Isoelectric Point: 6.8715

>T273301 WP_274907473.1 NZ_CP118607:5197787-5198206 [Pseudomonas sp. PSKL.D1]
MLRYMLDTNICIFTIKNKPQQVREAFNRHHGQMAISTVTLMELVYGAEKSAYPDRNLTIVEGFAARLEVVEYDSLAAEHS
GQLRAELAKAGTPIGPYDQLIAGHARARGLVLVTNNLREFQRVPGLRVEDWLISPTDSA

Download         Length: 420 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8522.40 Da        Isoelectric Point: 4.1834

>AT273301 WP_274907472.1 NZ_CP118607:5197557-5197787 [Pseudomonas sp. PSKL.D1]
MEQGAVFKSNRSQAIRLPKSVALPDEVTRVDIVAVGRTRIITPAGEAWDSWFDGNDVSPDFMAERDQPDDQEREGF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References