Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 4369810..4371455 Replicon chromosome
Accession NZ_CP118607
Organism Pseudomonas sp. PSKL.D1

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PVV54_RS19405 Protein ID WP_274906795.1
Coordinates 4369810..4370637 (+) Length 276 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PVV54_RS19410 Protein ID WP_274910468.1
Coordinates 4370643..4371455 (+) Length 271 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVV54_RS19380 (PVV54_19380) 4365798..4366634 + 837 WP_274910465.1 ABC transporter ATP-binding protein -
PVV54_RS19385 (PVV54_19385) 4366706..4367668 + 963 WP_274910466.1 ABC transporter substrate-binding protein -
PVV54_RS19390 (PVV54_19390) 4367697..4368473 + 777 WP_274906793.1 ABC transporter permease -
PVV54_RS19395 (PVV54_19395) 4368473..4369237 + 765 WP_274910467.1 SDR family oxidoreductase -
PVV54_RS19400 (PVV54_19400) 4369254..4369793 + 540 WP_274906794.1 cupin domain-containing protein -
PVV54_RS19405 (PVV54_19405) 4369810..4370637 + 828 WP_274906795.1 alpha/beta fold hydrolase Toxin
PVV54_RS19410 (PVV54_19410) 4370643..4371455 + 813 WP_274910468.1 IclR family transcriptional regulator Antitoxin
PVV54_RS19415 (PVV54_19415) 4371457..4372254 + 798 WP_274906796.1 SDR family oxidoreductase -
PVV54_RS19420 (PVV54_19420) 4372247..4373929 + 1683 WP_274906797.1 thiamine pyrophosphate-binding protein -
PVV54_RS19425 (PVV54_19425) 4373940..4374743 + 804 WP_274906798.1 aspartate dehydrogenase -
PVV54_RS19430 (PVV54_19430) 4374754..4376244 + 1491 WP_274906799.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(30-142)

Antitoxin

Transcription regulator IclR, C-terminal

(131-253)


Sequences

Toxin        


Download         Length: 276 a.a.        Molecular weight: 29068.26 Da        Isoelectric Point: 7.2007

>T273300 WP_274906795.1 NZ_CP118607:4369810-4370637 [Pseudomonas sp. PSKL.D1]
MPNLDLHFAERLLRLDGAQLAVRQAGSGEAVVLLHGIGSGAASWLQVATGLSERARVIAWDAPGYGQSTPLPMAAPRASD
YAARLLQALDALGVQRCMLVGHSLGALTACAFARQHPQRVSRLVLLSPARGYGAEPEQGQAVRAKRLHSLEQLGIEQMAR
ERSAHLLSANASAEALAWVQWNMARLQPHGYRQAIELLCGDYLLRYTPLAVACDVHCGSADGITRPEDCRALADALGAPF
HLIAGAGHACAIEQPDTVTGLLARALDASLTGSAP

Download         Length: 828 bp

Antitoxin


Download         Length: 271 a.a.        Molecular weight: 29753.23 Da        Isoelectric Point: 6.9621

>AT273300 WP_274910468.1 NZ_CP118607:4370643-4371455 [Pseudomonas sp. PSKL.D1]
MDNLKDNQDKYIVPGLERGLLLLCEFSRQNRTLTAPELARRLSLPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLRLGF
EYLASLELTELGQPLLARLCDHLNYPSNLVVRDGRSIVYVAKVSPPSVFSSAVTVGTRLPAHATVLGRILLADLSLAELR
ELYPEEHLEQYSPCTPKTVLELFNLVQADRLRGFVSGEGFFESTISTVAAPVRDASGQVVAALGLTIPTVQIGHVNFDNL
LGQVRGSADELSRLLNYRPGSGHVTALMRD

Download         Length: 813 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References