Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1588983..1589571 Replicon chromosome
Accession NZ_CP118607
Organism Pseudomonas sp. PSKL.D1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PVV54_RS06995 Protein ID WP_274909235.1
Coordinates 1589269..1589571 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PVV54_RS06990 Protein ID WP_274909234.1
Coordinates 1588983..1589276 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVV54_RS06960 (PVV54_06960) 1584207..1584467 - 261 Protein_1362 mechanosensitive ion channel family protein -
PVV54_RS06965 (PVV54_06965) 1584913..1585155 + 243 WP_274909229.1 hypothetical protein -
PVV54_RS06970 (PVV54_06970) 1585237..1585506 + 270 WP_274909230.1 DUF3077 domain-containing protein -
PVV54_RS06975 (PVV54_06975) 1585644..1586942 - 1299 WP_274909231.1 mechanosensitive ion channel family protein -
PVV54_RS06980 (PVV54_06980) 1587047..1588408 + 1362 WP_274909232.1 DEAD/DEAH box helicase -
PVV54_RS06985 (PVV54_06985) 1588588..1588860 - 273 WP_274909233.1 hypothetical protein -
PVV54_RS06990 (PVV54_06990) 1588983..1589276 - 294 WP_274909234.1 putative addiction module antidote protein Antitoxin
PVV54_RS06995 (PVV54_06995) 1589269..1589571 - 303 WP_274909235.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PVV54_RS07000 (PVV54_07000) 1589872..1590798 + 927 WP_274909236.1 DMT family transporter -
PVV54_RS07005 (PVV54_07005) 1590740..1591930 - 1191 WP_274909237.1 MFS transporter -
PVV54_RS07010 (PVV54_07010) 1592037..1592930 + 894 WP_274909238.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(6-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11313.10 Da        Isoelectric Point: 10.7302

>T273298 WP_274909235.1 NZ_CP118607:c1589571-1589269 [Pseudomonas sp. PSKL.D1]
MKKIESSSFRKWVIGLKDAKARVRIISRINRLMEGISGDVSPVGHGVSELRIHLGPGYRVYFHQSGDTLVILLCGGDKDS
QQRDIKAAHQILRAWRMQND

Download         Length: 303 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 4.7628

>AT273298 WP_274909234.1 NZ_CP118607:c1589276-1588983 [Pseudomonas sp. PSKL.D1]
MTDTFFEFDPADYLTTPEAIALFMTDALETGDASYVAKAVGVVARAKGMTELAKETGLSREQLYRSFSEHGNPTLKSFLA
VMKALGIDMTATPHLAR

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References