Detailed information of TA system TA273266

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): sanaTA/AbiEii-DUF6088
• Location: 1448126..1449473
• Replicon: chromosome
• Accession: NZ_CP118597
• Organism: Vibrio harveyi strain fish10

Toxin (Protein)

• Gene name: sanaT
• Uniprot ID: -
• Locus tag: PWW26_RS24265
• Protein ID: WP_274879198.1
• Coordinates: 1448532..1449473 (+)
• Length: 314 a.a.

Antitoxin (Protein)

• Gene name: sanaA
• Uniprot ID: -
• Locus tag: PWW26_RS24260
• Protein ID: WP_061007692.1
• Coordinates: 1448126..1448530 (+)
• Length: 135 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PWW26_RS24245	1445789..1446241	-	453	WP_021018079.1	hypothetical protein	-
PWW26_RS24250	1446822..1447064	+	243	WP_061007694.1	helix-turn-helix domain-containing protein	-
PWW26_RS24255	1447344..1447937	+	594	Protein_1274	tyrosine-type recombinase/integrase	-
PWW26_RS24260	1448126..1448530	+	405	WP_061007692.1	DUF6088 family protein	Antitoxin
PWW26_RS24265	1448532..1449473	+	942	WP_274879198.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
PWW26_RS24270	1449493..1451040	+	1548	WP_274879199.1	type I restriction-modification system subunit M	-
PWW26_RS24275	1451030..1452280	+	1251	WP_274879200.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (37-300)

Antitoxin

• Protein of unknown function DUF6088 (7-130)

Sequences

Toxin

Protein

• Length: 314 a.a.
• Molecular weight: 35674.18 Da
• Isoelectric Point: 6.1730

>T273266 WP_274879198.1 NZ_CP118597:1448532-1449473 [Vibrio harveyi]
MNTLKQQFLEVSDALELGNPAIIEKDYWVVALLAELAKVCPEHHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNPAFDE
LSRAKKKATRKACVNKIEQALTQSGRFNVETRSVRDEYRYVEFELKYPQQFSQAPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPQEVSAFDCVSIHATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLSMPELDSIDGLFKAVL
AEDIARFGNQHAEFVANPKQELQLGLKELEANAIFRQRFQDFVTPMVFNTDPHDFDTCFASFKRIAASLIEKI

Nucleotide

• Length: 942 bp

Antitoxin

Protein

• Length: 135 a.a.
• Molecular weight: 15154.52 Da
• Isoelectric Point: 10.4983

>AT273266 WP_061007692.1 NZ_CP118597:1448126-1448530 [Vibrio harveyi]
MTAVDRICQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALMRE
ILKMKGVDFEMDSLSLQSLSGSSTQIPSSIQYSWDPKQFNRKLVVGSRVLNLPS

Nucleotide

• Length: 405 bp