Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 5874188..5874698 Replicon chromosome
Accession NZ_CP118574
Organism Streptomyces sp. WZ-12

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PV796_RS25355 Protein ID WP_274915691.1
Coordinates 5874393..5874698 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PV796_RS25350 Protein ID WP_274915690.1
Coordinates 5874188..5874406 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PV796_RS25340 5870207..5871352 + 1146 WP_274915688.1 allantoicase -
PV796_RS25345 5871536..5874112 - 2577 WP_274915689.1 aminopeptidase N -
PV796_RS25350 5874188..5874406 + 219 WP_274915690.1 antitoxin Antitoxin
PV796_RS25355 5874393..5874698 + 306 WP_274915691.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PV796_RS25360 5874815..5875846 - 1032 WP_274915692.1 aspartate-semialdehyde dehydrogenase -
PV796_RS25365 5876052..5877065 - 1014 WP_274915693.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-99)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 10994.55 Da        Isoelectric Point: 9.6869

>T273243 WP_274915691.1 NZ_CP118574:5874393-5874698 [Streptomyces sp. WZ-12]
MRRGDIYLVDYAPTRGGEANKPRPAVVVSNDGANEVVDRTRRGVVTAVPLTTNVSRVYPFQVLLPADESGLLKDSKVQCE
QVRSLAPERLLRFLGSVPSSA

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 7979.60 Da        Isoelectric Point: 3.8382

>AT273243 WP_274915690.1 NZ_CP118574:5874188-5874406 [Streptomyces sp. WZ-12]
VVVAQEDVEFVDAYAAKRAVDSRSAVIHAAIEQLREAELRADYEAAFAEWDASEDAAFWDQFTGDGLTDEAR

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References