Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2655473..2655674 Replicon chromosome
Accession NZ_CP118567
Organism Enterobacter hormaechei strain 2020CK-00199

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2655478..2655581 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2655473..2655674 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXV21_RS12570 (PXV21_12570) 2651741..2653183 + 1443 WP_072202184.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PXV21_RS12575 (PXV21_12575) 2653288..2653527 + 240 WP_006811010.1 YebV family protein -
PXV21_RS12580 (PXV21_12580) 2653562..2654206 - 645 WP_022648462.1 protein-serine/threonine phosphatase -
PXV21_RS12585 (PXV21_12585) 2654374..2655354 + 981 WP_022648463.1 VirK/YbjX family protein -
PXV21_RS12590 (PXV21_12590) 2655400..2655597 + 198 WP_032609507.1 hypothetical protein -
- 2655473..2655674 + 202 - - Antitoxin
- 2655478..2655581 - 104 - - Toxin
PXV21_RS12595 (PXV21_12595) 2655723..2656061 - 339 WP_022648464.1 YebY family protein -
PXV21_RS12600 (PXV21_12600) 2656078..2656947 - 870 WP_022648465.1 copper homeostasis membrane protein CopD -
PXV21_RS12605 (PXV21_12605) 2656949..2657320 - 372 WP_022648466.1 CopC domain-containing protein YobA -
PXV21_RS12610 (PXV21_12610) 2657458..2657688 + 231 WP_003859784.1 DNA polymerase III subunit theta -
PXV21_RS12615 (PXV21_12615) 2657800..2658438 + 639 WP_022648467.1 nitrilase-related carbon-nitrogen hydrolase -
PXV21_RS12620 (PXV21_12620) 2658463..2659125 + 663 WP_022648468.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T273234 NZ_CP118567:c2655581-2655478 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 202 bp

>AT273234 NZ_CP118567:2655473-2655674 [Enterobacter hormaechei]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTGGT
CTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References