Detailed information of TA system TA273217

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 722622..724090
• Replicon: chromosome
• Accession: NZ_CP118547
• Organism: Stenotrophomonas maltophilia strain HT2

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: PWE35_RS03260
• Protein ID: WP_157803285.1
• Coordinates: 722622..723491 (-)
• Length: 290 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: PWE35_RS03265
• Protein ID: WP_032966430.1
• Coordinates: 723488..724090 (-)
• Length: 201 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PWE35_RS03240 (PWE35_03240)	718761..719378	-	618	WP_154329236.1	metal-dependent hydrolase	-
PWE35_RS03245 (PWE35_03245)	719489..719857	-	369	WP_181453355.1	YraN family protein	-
PWE35_RS03250 (PWE35_03250)	719847..721568	-	1722	WP_274850046.1	penicillin-binding protein activator	-
PWE35_RS03255 (PWE35_03255)	721650..722468	+	819	WP_060381104.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
PWE35_RS03260 (PWE35_03260)	722622..723491	-	870	WP_157803285.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
PWE35_RS03265 (PWE35_03265)	723488..724090	-	603	WP_032966430.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
PWE35_RS03275 (PWE35_03275)	724841..725320	-	480	WP_100438877.1	DM13 domain-containing protein	-
PWE35_RS03280 (PWE35_03280)	725638..726390	-	753	WP_274850047.1	NRDE family protein	-
PWE35_RS03285 (PWE35_03285)	726759..727160	+	402	WP_008266948.1	division/cell wall cluster transcriptional repressor MraZ	-
PWE35_RS03290 (PWE35_03290)	727175..728143	+	969	WP_012479154.1	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	-
PWE35_RS03295 (PWE35_03295)	728140..728403	+	264	WP_005408074.1	cell division protein FtsL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	701865..725320	23455

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (40-268)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (12-53)

Sequences

Toxin

Protein

• Length: 290 a.a.
• Molecular weight: 32579.23 Da
• Isoelectric Point: 6.3012

>T273217 WP_157803285.1 NZ_CP118547:c723491-722622 [Stenotrophomonas maltophilia]
VTHSPPLPQRVASIRQRLLDLARSRGEDFQFVLDRFAVERLLYRLSASRYRDQFLLKGAMLFAVWFDAPHRPTRDADFLR
FGSADPDHLLHIARSLCAIPDDDGLCFDPGSIAIEATREEAEYEGLRIRLTAHLGRSRCHVQWDVGFGDAVTPPPPEIAY
PVMLDGFPLPCLHVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALVREDAMDRPHLVAAIGATFDRRRTPAPPPLPYG
LTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTTVQS

Nucleotide

• Length: 870 bp

Antitoxin

Protein

• Length: 201 a.a.
• Molecular weight: 22331.07 Da
• Isoelectric Point: 11.2557

>AT273217 WP_032966430.1 NZ_CP118547:c724090-723488 [Stenotrophomonas maltophilia]
MGNAEANARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERNSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSAKTLNAGLEERRVGKRLIYVSNVAKTVVDCFKFRNLVGLDV
AIEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Nucleotide

• Length: 603 bp