Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 306759..307407 Replicon chromosome
Accession NZ_CP118547
Organism Stenotrophomonas maltophilia strain HT2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PWE35_RS01375 Protein ID WP_005407702.1
Coordinates 306759..307064 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PWE35_RS01380 Protein ID WP_005407703.1
Coordinates 307105..307407 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWE35_RS01350 (PWE35_01350) 302033..302893 + 861 WP_262101535.1 SPOR domain-containing protein -
PWE35_RS01360 (PWE35_01360) 303487..304158 - 672 WP_005407700.1 hypothetical protein -
PWE35_RS01365 (PWE35_01365) 304249..305754 - 1506 WP_005407701.1 hypothetical protein -
PWE35_RS01375 (PWE35_01375) 306759..307064 + 306 WP_005407702.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PWE35_RS01380 (PWE35_01380) 307105..307407 + 303 WP_005407703.1 putative addiction module antidote protein Antitoxin
PWE35_RS01385 (PWE35_01385) 307665..307964 - 300 WP_005407704.1 hypothetical protein -
PWE35_RS01390 (PWE35_01390) 308045..308452 - 408 WP_043035194.1 hypothetical protein -
PWE35_RS01395 (PWE35_01395) 309043..309813 + 771 WP_005411960.1 DUF3011 domain-containing protein -
PWE35_RS01400 (PWE35_01400) 309838..310185 - 348 WP_005411961.1 hypothetical protein -
PWE35_RS01405 (PWE35_01405) 310316..311236 + 921 WP_005407709.1 arginase -
PWE35_RS01410 (PWE35_01410) 311397..311534 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
PWE35_RS01415 (PWE35_01415) 311743..311964 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11444.15 Da        Isoelectric Point: 10.9897

>T273216 WP_005407702.1 NZ_CP118547:306759-307064 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSELRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARALRASNWL

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10703.27 Da        Isoelectric Point: 7.2780

>AT273216 WP_005407703.1 NZ_CP118547:307105-307407 [Stenotrophomonas maltophilia]
MAIKKKVELEAFDVAEHLHTPKEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FSTILKVTRALGVRLHASAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References