Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
Location | 1227556..1228352 | Replicon | chromosome |
Accession | NZ_CP118539 | ||
Organism | Xylella fastidiosa strain ICMP 15197 |
Toxin (Protein)
Gene name | VbhT | Uniprot ID | Q87CQ8 |
Locus tag | PXH81_RS05505 | Protein ID | WP_004088112.1 |
Coordinates | 1227556..1228167 (-) | Length | 204 a.a. |
Antitoxin (Protein)
Gene name | VbhA | Uniprot ID | B2I551 |
Locus tag | PXH81_RS05510 | Protein ID | WP_004088114.1 |
Coordinates | 1228164..1228352 (-) | Length | 63 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PXH81_RS05460 (PXH81_05460) | 1223011..1223898 | - | 888 | WP_012382597.1 | YdaU family protein | - |
PXH81_RS05465 (PXH81_05465) | 1223895..1224683 | - | 789 | WP_011097897.1 | Bro-N domain-containing protein | - |
PXH81_RS05470 (PXH81_05470) | 1224680..1225312 | - | 633 | WP_004088094.1 | Bro-N domain-containing protein | - |
PXH81_RS05475 (PXH81_05475) | 1225309..1225572 | - | 264 | WP_228446177.1 | hypothetical protein | - |
PXH81_RS05480 (PXH81_05480) | 1225590..1225805 | - | 216 | WP_012382598.1 | hypothetical protein | - |
PXH81_RS05485 (PXH81_05485) | 1225835..1226023 | - | 189 | WP_004088102.1 | hypothetical protein | - |
PXH81_RS05490 (PXH81_05490) | 1226051..1226242 | - | 192 | WP_004088104.1 | hypothetical protein | - |
PXH81_RS05495 (PXH81_05495) | 1226501..1226746 | - | 246 | WP_004088108.1 | hypothetical protein | - |
PXH81_RS05500 (PXH81_05500) | 1226831..1227505 | + | 675 | WP_004088110.1 | helix-turn-helix transcriptional regulator | - |
PXH81_RS05505 (PXH81_05505) | 1227556..1228167 | - | 612 | WP_004088112.1 | Fic/DOC family protein | Toxin |
PXH81_RS05510 (PXH81_05510) | 1228164..1228352 | - | 189 | WP_004088114.1 | antitoxin VbhA family protein | Antitoxin |
PXH81_RS05515 (PXH81_05515) | 1228744..1229280 | + | 537 | WP_038233020.1 | hypothetical protein | - |
PXH81_RS05520 (PXH81_05520) | 1229277..1229690 | + | 414 | WP_004088056.1 | DUF1566 domain-containing protein | - |
PXH81_RS05525 (PXH81_05525) | 1229687..1230088 | + | 402 | WP_004088054.1 | hypothetical protein | - |
PXH81_RS05530 (PXH81_05530) | 1230085..1230234 | + | 150 | WP_012382602.1 | hypothetical protein | - |
PXH81_RS05535 (PXH81_05535) | 1230452..1230598 | + | 147 | WP_225621633.1 | hypothetical protein | - |
PXH81_RS05540 (PXH81_05540) | 1230621..1230812 | + | 192 | WP_012382603.1 | hypothetical protein | - |
PXH81_RS05545 (PXH81_05545) | 1230833..1231177 | + | 345 | WP_004088346.1 | hypothetical protein | - |
PXH81_RS05550 (PXH81_05550) | 1231217..1232038 | + | 822 | WP_004088345.1 | DUF2303 family protein | - |
PXH81_RS05555 (PXH81_05555) | 1232054..1232980 | + | 927 | WP_004088344.1 | phage recombination protein Bet | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 1197384..1238102 | 40718 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 204 a.a. Molecular weight: 22832.60 Da Isoelectric Point: 5.1271
>T273185 WP_004088112.1 NZ_CP118539:c1228167-1227556 [Xylella fastidiosa]
MKYAGDRGDPYLDSETGVLRNLLGIRDQGGLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
MKYAGDRGDPYLDSETGVLRNLLGIRDQGGLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
Download Length: 612 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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