Detailed information of TA system TA273140

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 2846988..2847535
• Replicon: chromosome
• Accession: NZ_CP118528
• Organism: Vibrio harveyi strain 94/17

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PWS04_RS13745
• Protein ID: WP_258455559.1
• Coordinates: 2847233..2847535 (+)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A454B3H2
• Locus tag: PWS04_RS13740
• Protein ID: WP_005445660.1
• Coordinates: 2846988..2847245 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PWS04_RS13690	2842114..2842365	+	252	WP_274791738.1	hypothetical protein	-
PWS04_RS13695	2842484..2842577	+	94	Protein_2592	DUF3265 domain-containing protein	-
PWS04_RS13700	2842608..2843273	+	666	WP_274791739.1	hypothetical protein	-
PWS04_RS13705	2843433..2844818	+	1386	WP_274791740.1	hypothetical protein	-
PWS04_RS13710	2844957..2845256	+	300	WP_005536942.1	hypothetical protein	-
PWS04_RS13715	2845253..2845321	+	69	Protein_2596	DUF3265 domain-containing protein	-
PWS04_RS13720	2845458..2845901	+	444	WP_274791741.1	GNAT family N-acetyltransferase	-
PWS04_RS13725	2846196..2846420	+	225	WP_274791742.1	BrnT family toxin	-
PWS04_RS13730	2846458..2846637	+	180	WP_017190351.1	hypothetical protein	-
PWS04_RS13735	2846634..2846789	+	156	WP_017190350.1	hypothetical protein	-
PWS04_RS13740	2846988..2847245	+	258	WP_005445660.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
PWS04_RS13745	2847233..2847535	+	303	WP_258455559.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PWS04_RS13750	2847579..2847731	-	153	Protein_2603	IS30 family transposase	-
PWS04_RS13755	2848060..2848332	+	273	WP_050903611.1	hypothetical protein	-
PWS04_RS13760	2848326..2848445	+	120	WP_080585338.1	DUF3265 domain-containing protein	-
PWS04_RS13765	2848501..2848917	+	417	WP_274791743.1	hypothetical protein	-
PWS04_RS13770	2849125..2849556	+	432	WP_045490299.1	GNAT family N-acetyltransferase	-
PWS04_RS13775	2850803..2851054	+	252	WP_017817975.1	DUF2442 domain-containing protein	-
PWS04_RS13780	2851720..2851965	+	246	WP_222326331.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2816228..2853598	37370
	-	inside	Integron	-	-	2815626..2845901	30275

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-69)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11623.59 Da
• Isoelectric Point: 7.9971

>T273140 WP_258455559.1 NZ_CP118528:2847233-2847535 [Vibrio harveyi]
MAEIIWTEPALSDLNDIAEYIALENIVAAKQLVQTIFSKVERLQTFPESGRIPPDLKHLSYREVVVNPCRVFYKQDGDKV
FILFVMRAERGLRKFLLNKQ

Nucleotide

• Length: 303 bp

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9548.06 Da
• Isoelectric Point: 7.3177

>AT273140 WP_005445660.1 NZ_CP118528:2846988-2847245 [Vibrio harveyi]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKVVSHDEAKGKM
SKWLK

Nucleotide

• Length: 258 bp

Structures

Antitoxin

• AlphaFold DB: A0A454B3H2