Detailed information of TA system TA273137

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): sanaTA/AbiEii-DUF6088
• Location: 2634592..2635930
• Replicon: chromosome
• Accession: NZ_CP118496
• Organism: Pseudoalteromonas rhizosphaerae strain hCg-42

Toxin (Protein)

• Gene name: sanaT
• Uniprot ID: -
• Locus tag: PVK79_RS11055
• Protein ID: WP_257326742.1
• Coordinates: 2634980..2635930 (+)
• Length: 317 a.a.

Antitoxin (Protein)

• Gene name: sanaA
• Uniprot ID: -
• Locus tag: PVK79_RS11050
• Protein ID: WP_182794393.1
• Coordinates: 2634592..2634990 (+)
• Length: 133 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PVK79_RS11040	2631907..2632662	-	756	WP_257323996.1	IS21-like element helper ATPase IstB	-
PVK79_RS11045	2632674..2634224	-	1551	WP_257324076.1	IS21 family transposase	-
PVK79_RS11050	2634592..2634990	+	399	WP_182794393.1	DUF6088 family protein	Antitoxin
PVK79_RS11055	2634980..2635930	+	951	WP_257326742.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
PVK79_RS11060	2636473..2637246	-	774	WP_182762799.1	IS21-like element helper ATPase IstB	-
PVK79_RS11065	2637243..2638277	-	1035	WP_182762801.1	IS21 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	2631907..2637246	5339

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (36-299)

Antitoxin

• Protein of unknown function DUF6088 (15-71)

Sequences

Toxin

Protein

• Length: 317 a.a.
• Molecular weight: 36208.42 Da
• Isoelectric Point: 6.3055

>T273137 WP_257326742.1 NZ_CP118496:2634980-2635930 [Pseudoalteromonas rhizosphaerae]
MQVDSDLFLDVADALGMGNPAIVEKDYYVVALLKLLSELFFDTHFLVFSGGTALTKSGIKTHRMSEDVDIKIIPKDLAAN
TSKTKRRKARKALHLQLIDAINSYDYFSVENAPTVFDEYRYQQIDIRYPQAHSKAPCLRPFIKLELIETLLFDNVQSRNI
SSLVNEITQQAPEVPLMDFSSIKSTQAEKLVSMLRRTASFARDNRRDDDPALIRHIYDTYYIQQAGLANVQDVVPLVQKV
IAEDITRYGNQHAEFMENPITELRFALGVLQANSIYEARFNKYVVPMVYGNHSLNWEHAFDVFKLYCDQVLNNIKL

Nucleotide

• Length: 951 bp

Antitoxin

Protein

• Length: 133 a.a.
• Molecular weight: 14705.89 Da
• Isoelectric Point: 10.5414

>AT273137 WP_182794393.1 NZ_CP118496:2634592-2634990 [Pseudoalteromonas rhizosphaerae]
MTIASKVTTRINRSRRYVFERADFADIAGYDQVGRVLKKLVDSGQLLRIGYGLYTKARENRITGKLMPASPAGADGVILE
AIEKLGVEYQFDEFSQRSLNGESLQVPASFKIMTNSRFKRKIVVNNSAINAS

Nucleotide

• Length: 399 bp