Detailed information of TA system TA273136

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 2613593..2615008
• Replicon: chromosome
• Accession: NZ_CP118496
• Organism: Pseudoalteromonas rhizosphaerae strain hCg-42

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: PVK79_RS10985
• Protein ID: WP_145238779.1
• Coordinates: 2613593..2614483 (-)
• Length: 297 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: PVK79_RS10990
• Protein ID: WP_145238776.1
• Coordinates: 2614484..2615008 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PVK79_RS10975	2611372..2612406	+	1035	WP_257324812.1	IS21 family transposase	-
PVK79_RS10980	2612403..2613176	+	774	WP_182762799.1	IS21-like element helper ATPase IstB	-
PVK79_RS10985	2613593..2614483	-	891	WP_145238779.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
PVK79_RS10990	2614484..2615008	-	525	WP_145238776.1	hypothetical protein	Antitoxin
PVK79_RS10995	2615794..2616399	+	606	WP_257326733.1	class I SAM-dependent methyltransferase	-
PVK79_RS11000	2616392..2619346	+	2955	WP_257326734.1	DEAD/DEAH box helicase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2612403..2613176	773

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (32-258)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 297 a.a.
• Molecular weight: 33892.83 Da
• Isoelectric Point: 6.6133

>T273136 WP_145238779.1 NZ_CP118496:c2614483-2613593 [Pseudoalteromonas rhizosphaerae]
MLTEYIRQIIAANPEYAGVTPVIEKEILHHDIMAAMVKQGVMPSLTFIGGTSLRLCHNSSRLSEDLDFNGGHDFKPSSFS
GLEVEIQKYIQNKYEVQVWVNKPAEDNQANTSSWKISIEKESNRPDLPRQKMHIDICAIPSFDIEKRPLINHYNIVAPTE
GLLIPVQSLTETLADKFIALAYPARRIKPRDVWDIVWIKQRGVAVSKQLINKKLVARGKTNEDFIEALTIQLDKLQHDDE
VRKDFNIEMSRFIPNQIKERTIDNPDYWPYVQSEISTMSLSILNNGIKNNKFDMGS

Nucleotide

• Length: 891 bp

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19317.54 Da
• Isoelectric Point: 10.1402

>AT273136 WP_145238776.1 NZ_CP118496:c2615008-2614484 [Pseudoalteromonas rhizosphaerae]
MNKAERLLAILASSVKAGGGIHTSAELAFMMAEKPTPAFTKFLTDNVNKGLLRRVCNGIFESTLTPPDPTTAIYKIVKKL
RGDVLNYISLESQLSYTGDISQILMDRLTVITKGRSGTFSTPYGVIELTHTKKPIDKFAKNLYFDKSIKMYRANTLQAIA
DLKACNRNVHMLEN

Nucleotide

• Length: 525 bp