Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | sanaTA/AbiEii-DUF6088 |
| Location | 1483895..1485242 | Replicon | chromosome |
| Accession | NZ_CP118439 | ||
| Organism | Vibrio vulnificus strain 1908-10 | ||
Toxin (Protein)
| Gene name | sanaT | Uniprot ID | - |
| Locus tag | PVE41_RS21815 | Protein ID | WP_015727856.1 |
| Coordinates | 1484301..1485242 (+) | Length | 314 a.a. |
Antitoxin (Protein)
| Gene name | sanaA | Uniprot ID | A0A3Q0KXE1 |
| Locus tag | PVE41_RS21810 | Protein ID | WP_011081161.1 |
| Coordinates | 1483895..1484299 (+) | Length | 135 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PVE41_RS21790 (PVE41_21790) | 1479091..1479549 | + | 459 | WP_045598334.1 | hypothetical protein | - |
| PVE41_RS21795 (PVE41_21795) | 1479739..1480485 | + | 747 | WP_198434322.1 | carbon-nitrogen hydrolase family protein | - |
| PVE41_RS21800 (PVE41_21800) | 1480985..1481749 | + | 765 | WP_118894273.1 | nucleotidyltransferase domain-containing protein | - |
| PVE41_RS21805 (PVE41_21805) | 1481802..1483562 | - | 1761 | WP_282500337.1 | ABC transporter ATP-binding protein/permease | - |
| PVE41_RS21810 (PVE41_21810) | 1483895..1484299 | + | 405 | WP_011081161.1 | DUF6088 family protein | Antitoxin |
| PVE41_RS21815 (PVE41_21815) | 1484301..1485242 | + | 942 | WP_015727856.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| PVE41_RS21820 (PVE41_21820) | 1485629..1487215 | + | 1587 | WP_045622347.1 | AAA family ATPase | - |
| PVE41_RS21825 (PVE41_21825) | 1487200..1488231 | + | 1032 | WP_118894275.1 | DNA helicase UvrD | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1476658..1488231 | 11573 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 314 a.a. Molecular weight: 36057.46 Da Isoelectric Point: 5.3076
>T273129 WP_015727856.1 NZ_CP118439:1484301-1485242 [Vibrio vulnificus]
MNALKQQFLEVSDALELGNPAIIEKDFWVVALLAELAKVSPEYHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKGVRKAWVNEIEQAITHSERFTVETRSVRDEYRYVEFELRYPQQFSQVPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPHEVSSFDCVSVYATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLTMSELNSIDGLFKAVL
EEDIARFGNQHAEFVANPKQELQLGLKELEENPIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI
MNALKQQFLEVSDALELGNPAIIEKDFWVVALLAELAKVSPEYHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKGVRKAWVNEIEQAITHSERFTVETRSVRDEYRYVEFELRYPQQFSQVPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPHEVSSFDCVSVYATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLTMSELNSIDGLFKAVL
EEDIARFGNQHAEFVANPKQELQLGLKELEENPIFRQRFQDFVTPMVFNTEPHDFDTCFASFKRIAASLIEKI
Download Length: 942 bp
Antitoxin
Download Length: 135 a.a. Molecular weight: 15175.47 Da Isoelectric Point: 10.6526
>AT273129 WP_011081161.1 NZ_CP118439:1483895-1484299 [Vibrio vulnificus]
MTAVDRIYQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALVRE
ILKMKGVDFEMDSLSQQSLSGASTQIPSSVHYSWNPKQFNRKLVVGSRVLNLPS
MTAVDRIYQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALVRE
ILKMKGVDFEMDSLSQQSLSGASTQIPSSVHYSWNPKQFNRKLVVGSRVLNLPS
Download Length: 405 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|