273128

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1060954..1061513 Replicon chromosome
Accession NZ_CP118439
Organism Vibrio vulnificus strain 1908-10

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PVE41_RS20045 Protein ID WP_047111817.1
Coordinates 1061235..1061513 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3Q0L0M2
Locus tag PVE41_RS20040 Protein ID WP_011082348.1
Coordinates 1060954..1061238 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVE41_RS20010 (PVE41_20010) 1056099..1057292 + 1194 WP_011082341.1 glycine C-acetyltransferase -
PVE41_RS20015 (PVE41_20015) 1057323..1058354 + 1032 WP_011082342.1 L-threonine 3-dehydrogenase -
PVE41_RS20020 (PVE41_20020) 1058434..1058934 - 501 WP_065090958.1 opioid growth factor receptor-related protein -
PVE41_RS20025 (PVE41_20025) 1059012..1059275 - 264 WP_011082346.1 hypothetical protein -
PVE41_RS20030 (PVE41_20030) 1059460..1059993 - 534 WP_088428331.1 hypothetical protein -
PVE41_RS20035 (PVE41_20035) 1060128..1060736 - 609 WP_011151714.1 hypothetical protein -
PVE41_RS20040 (PVE41_20040) 1060954..1061238 + 285 WP_011082348.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PVE41_RS20045 (PVE41_20045) 1061235..1061513 + 279 WP_047111817.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
PVE41_RS20050 (PVE41_20050) 1061542..1061632 - 91 Protein_882 DUF3265 domain-containing protein -
PVE41_RS20055 (PVE41_20055) 1061668..1063452 - 1785 WP_065090960.1 NACHT domain-containing protein -
PVE41_RS20060 (PVE41_20060) 1063497..1063598 - 102 WP_081280401.1 DUF3265 domain-containing protein -
PVE41_RS20065 (PVE41_20065) 1063616..1064176 - 561 WP_065090961.1 hypothetical protein -
PVE41_RS20070 (PVE41_20070) 1065230..1065745 - 516 WP_072610557.1 lipocalin family protein -
PVE41_RS20075 (PVE41_20075) 1065861..1066484 - 624 WP_015727543.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 1060128..1064176 4048


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-45)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10951.63 Da        Isoelectric Point: 4.3430

>T273128 WP_047111817.1 NZ_CP118439:1061235-1061513 [Vibrio vulnificus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIETKVENLLEQPLMGVQRDSIRGRLLIIPEISMVISYWVEGDIIRVM
RVLHQKQKFPTD

Download         Length: 279 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11083.43 Da        Isoelectric Point: 9.2167

>AT273128 WP_011082348.1 NZ_CP118439:1060954-1061238 [Vibrio vulnificus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFIEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3Q0L0M2

References