Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-couple_hipB |
Location | 2529843..2531671 | Replicon | chromosome |
Accession | NZ_CP118438 | ||
Organism | Vibrio vulnificus strain 1908-10 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | - |
Locus tag | PVE41_RS12105 | Protein ID | WP_013572329.1 |
Coordinates | 2530310..2531671 (-) | Length | 454 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | - |
Locus tag | PVE41_RS12100 | Protein ID | WP_029786578.1 |
Coordinates | 2529843..2530325 (-) | Length | 161 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PVE41_RS12080 (PVE41_12080) | 2525856..2526410 | + | 555 | WP_060532377.1 | hypothetical protein | - |
PVE41_RS12085 (PVE41_12085) | 2526412..2527167 | + | 756 | WP_061058291.1 | NRDE family protein | - |
PVE41_RS12090 (PVE41_12090) | 2527182..2527619 | + | 438 | WP_011078502.1 | YHS domain-containing (seleno)protein | - |
PVE41_RS12095 (PVE41_12095) | 2527662..2529404 | + | 1743 | WP_072610740.1 | GNAT family N-acyltransferase | - |
PVE41_RS12100 (PVE41_12100) | 2529843..2530325 | - | 483 | WP_029786578.1 | helix-turn-helix transcriptional regulator | Antitoxin |
PVE41_RS12105 (PVE41_12105) | 2530310..2531671 | - | 1362 | WP_013572329.1 | type II toxin-antitoxin system HipA family toxin | Toxin |
PVE41_RS12115 (PVE41_12115) | 2532559..2533044 | - | 486 | WP_011078466.1 | SsrA-binding protein SmpB | - |
PVE41_RS12120 (PVE41_12120) | 2533160..2533591 | + | 432 | WP_026050324.1 | SRPBCC family protein | - |
PVE41_RS12125 (PVE41_12125) | 2533588..2533941 | + | 354 | WP_011078464.1 | RnfH family protein | - |
PVE41_RS12130 (PVE41_12130) | 2534037..2534396 | - | 360 | WP_011078463.1 | outer membrane protein assembly factor BamE | - |
PVE41_RS12135 (PVE41_12135) | 2534575..2536239 | - | 1665 | WP_045595834.1 | DNA repair protein RecN | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 454 a.a. Molecular weight: 51441.20 Da Isoelectric Point: 4.8182
>T273127 WP_013572329.1 NZ_CP118438:c2531671-2530310 [Vibrio vulnificus]
MEELTVQAFIRSEWIDIGIISFPKSSQHNFRVTELNYLSDYALEHHDKDDFHAVSLNHPVSFFFDDMGKPGWLKFLDDIM
PSGASRRYWVKHLDIEDLSSDEQDYVLLKFGTMSPIGNLRIKDSLPERYEVADNLYFSVDDVKNRAGDFLDYAQQRGAAA
GGATGAGGEAPKLILRCGFDHGSGSEKIWIDPYQDDNSNHDLHYLVKYPRGSRSTIDCNILRAEFYFYHELTEMGVETIS
TDGMRLEEGLNYPSLWLPRFDVQIIEQQIERFGMESVYSILNKGAGVTLDHETTIRTLIEKITESNMVKHQGYRFDTQAF
VIEWVKRDLLNILFGNSDNHGRNTSFLKGDGVIKLAPVYDFAPMKADPEGIPRTTKWKAPLEVGGTYDFIGIADTLSDLV
PKEVLLQELEVTASKCIDLKQRLALRGVPEQILEMPAVGLNHISEKLTKWGLL
MEELTVQAFIRSEWIDIGIISFPKSSQHNFRVTELNYLSDYALEHHDKDDFHAVSLNHPVSFFFDDMGKPGWLKFLDDIM
PSGASRRYWVKHLDIEDLSSDEQDYVLLKFGTMSPIGNLRIKDSLPERYEVADNLYFSVDDVKNRAGDFLDYAQQRGAAA
GGATGAGGEAPKLILRCGFDHGSGSEKIWIDPYQDDNSNHDLHYLVKYPRGSRSTIDCNILRAEFYFYHELTEMGVETIS
TDGMRLEEGLNYPSLWLPRFDVQIIEQQIERFGMESVYSILNKGAGVTLDHETTIRTLIEKITESNMVKHQGYRFDTQAF
VIEWVKRDLLNILFGNSDNHGRNTSFLKGDGVIKLAPVYDFAPMKADPEGIPRTTKWKAPLEVGGTYDFIGIADTLSDLV
PKEVLLQELEVTASKCIDLKQRLALRGVPEQILEMPAVGLNHISEKLTKWGLL
Download Length: 1362 bp
Antitoxin
Download Length: 161 a.a. Molecular weight: 17535.05 Da Isoelectric Point: 10.8446
>AT273127 WP_029786578.1 NZ_CP118438:c2530325-2529843 [Vibrio vulnificus]
MGATMNKPSNKESVQDTVARLRANRNQHQPKTGTDATHSTKERSQLNTPTRSKTSKNAKAVSAAERKTEANKIIKHLLLG
ELTQGQALKSLRINILGLKQDVFARLVDVSRKTLSDIENDRGSYNTEILNKVFKPFGLKVGMLPSSPDVLKSLLIDGEAG
MGATMNKPSNKESVQDTVARLRANRNQHQPKTGTDATHSTKERSQLNTPTRSKTSKNAKAVSAAERKTEANKIIKHLLLG
ELTQGQALKSLRINILGLKQDVFARLVDVSRKTLSDIENDRGSYNTEILNKVFKPFGLKVGMLPSSPDVLKSLLIDGEAG
Download Length: 483 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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