Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1954582..1954727 Replicon chromosome
Accession NZ_CP118398
Organism Klebsiella pneumoniae strain 2020CK-00223

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1954618..1954720 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1954582..1954727 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWK27_RS09740 (PWK27_09740) 1949712..1951772 + 2061 WP_004151449.1 oligopeptidase B -
PWK27_RS09745 (PWK27_09745) 1951776..1952435 - 660 WP_002911407.1 exodeoxyribonuclease X -
PWK27_RS09750 (PWK27_09750) 1952514..1952744 - 231 WP_002911406.1 DNA polymerase III subunit theta -
PWK27_RS09755 (PWK27_09755) 1952857..1953231 + 375 WP_004151448.1 CopC domain-containing protein YobA -
PWK27_RS09760 (PWK27_09760) 1953235..1954104 + 870 WP_104158933.1 copper homeostasis membrane protein CopD -
PWK27_RS09765 (PWK27_09765) 1954121..1954459 + 339 WP_016529031.1 YebY family protein -
- 1954582..1954727 - 146 - - Antitoxin
- 1954618..1954720 + 103 - - Toxin
PWK27_RS09770 (PWK27_09770) 1955097..1955237 - 141 Protein_1909 Ecr family regulatory small membrane protein -
PWK27_RS09775 (PWK27_09775) 1955342..1956310 - 969 WP_004151446.1 VirK/YbjX family protein -
PWK27_RS09780 (PWK27_09780) 1956467..1957120 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
PWK27_RS09785 (PWK27_09785) 1957117..1957308 - 192 WP_002911395.1 YebW family protein -
PWK27_RS09790 (PWK27_09790) 1957406..1957645 - 240 WP_002911393.1 YebV family protein -
PWK27_RS09795 (PWK27_09795) 1957761..1959194 - 1434 WP_232553776.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T273095 NZ_CP118398:1954618-1954720 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCGTTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT273095 NZ_CP118398:c1954727-1954582 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAACGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References