Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2210630..2210831 Replicon chromosome
Accession NZ_CP118383
Organism Enterobacter hormaechei strain 2020CK-00224

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2210635..2210738 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2210630..2210831 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWH45_RS10565 (PWH45_10565) 2206890..2208338 + 1449 WP_195207010.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PWH45_RS10570 (PWH45_10570) 2208445..2208684 + 240 WP_003859885.1 YebV family protein -
PWH45_RS10575 (PWH45_10575) 2208719..2209363 - 645 WP_015570293.1 protein-serine/threonine phosphatase -
PWH45_RS10580 (PWH45_10580) 2209531..2210511 + 981 WP_047747105.1 VirK/YbjX family protein -
PWH45_RS10585 (PWH45_10585) 2210557..2210754 + 198 WP_032609507.1 hypothetical protein -
- 2210630..2210831 + 202 - - Antitoxin
- 2210635..2210738 - 104 - - Toxin
PWH45_RS10590 (PWH45_10590) 2210880..2211218 - 339 WP_003859787.1 YebY family protein -
PWH45_RS10595 (PWH45_10595) 2211235..2212104 - 870 WP_017693249.1 copper homeostasis membrane protein CopD -
PWH45_RS10600 (PWH45_10600) 2212106..2212477 - 372 WP_017384342.1 CopC domain-containing protein YobA -
PWH45_RS10605 (PWH45_10605) 2212615..2212845 + 231 WP_003859784.1 DNA polymerase III subunit theta -
PWH45_RS10610 (PWH45_10610) 2212957..2213607 + 651 WP_015570289.1 carbon-nitrogen hydrolase family protein -
PWH45_RS10615 (PWH45_10615) 2213632..2214294 + 663 WP_015570288.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T273072 NZ_CP118383:c2210738-2210635 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 202 bp

>AT273072 NZ_CP118383:2210630-2210831 [Enterobacter hormaechei]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGCAAAAGTGGT
CTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References