Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 3386584..3387317 Replicon chromosome
Accession NZ_CP118279
Organism Enterobacter hormaechei strain LG3

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag LNGFDJGK_RS16145 Protein ID WP_023480671.1
Coordinates 3386988..3387317 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag LNGFDJGK_RS16140 Protein ID WP_086722662.1
Coordinates 3386584..3386934 (+) Length 117 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNGFDJGK_RS16095 (LNGFDJGK_03181) 3381881..3382585 + 705 WP_251997742.1 WYL domain-containing protein -
LNGFDJGK_RS16100 (LNGFDJGK_03182) 3382585..3383154 + 570 WP_004929046.1 hypothetical protein -
LNGFDJGK_RS16105 (LNGFDJGK_03183) 3383191..3383643 + 453 WP_063925494.1 hypothetical protein -
LNGFDJGK_RS16110 (LNGFDJGK_03184) 3383640..3384089 + 450 WP_251997743.1 IrmA family protein -
LNGFDJGK_RS16115 (LNGFDJGK_03185) 3384161..3384391 + 231 WP_063925496.1 DUF905 domain-containing protein -
LNGFDJGK_RS16120 (LNGFDJGK_03186) 3384490..3385311 + 822 WP_251997744.1 DUF932 domain-containing protein -
LNGFDJGK_RS16125 (LNGFDJGK_03187) 3385342..3385785 + 444 WP_152049149.1 antirestriction protein -
LNGFDJGK_RS16130 (LNGFDJGK_03188) 3385798..3386340 + 543 WP_086722664.1 DNA repair protein RadC -
LNGFDJGK_RS16135 (LNGFDJGK_03189) 3386337..3386558 + 222 WP_097446462.1 DUF987 family protein -
LNGFDJGK_RS16140 (LNGFDJGK_03190) 3386584..3386934 + 351 WP_086722662.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LNGFDJGK_RS16145 (LNGFDJGK_03191) 3386988..3387317 + 330 WP_023480671.1 TA system toxin CbtA family protein Toxin
LNGFDJGK_RS16150 (LNGFDJGK_03192) 3387591..3388901 - 1311 WP_023323626.1 amidase family protein -
LNGFDJGK_RS16155 (LNGFDJGK_03193) 3388955..3390250 - 1296 WP_045335642.1 histidinol dehydrogenase -
LNGFDJGK_RS16160 (LNGFDJGK_03194) 3390251..3391393 - 1143 WP_015571629.1 ester cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3361921..3387317 25396
- inside Genomic island - - 3344465..3387317 42852


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(17-116)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12338.07 Da        Isoelectric Point: 7.3216

>T273057 WP_023480671.1 NZ_CP118279:3386988-3387317 [Enterobacter hormaechei]
MQTLSSHPTQAAQPCLSPIEIWQCLLTHLLSQHYGLTLNDTPFSNETTIREHIDAGVSLSDAVNFLVERYGLVRIDRKGF
SWQEQTPYISVVDILRARRSTGLLKTNVK

Download         Length: 330 bp

Antitoxin


Download         Length: 117 a.a.        Molecular weight: 12989.76 Da        Isoelectric Point: 5.4856

>AT273057 WP_086722662.1 NZ_CP118279:3386584-3386934 [Enterobacter hormaechei]
MNNHSESGAIPENPACQQWGLKRAMTPCFGARLVQEGDRLHFLADRAGFNGAFSDEHALRLDQAFPLMLKQLELMLISSE
LNPRYQHCVTLYHNGLTCEADTLGSCGYVYIAIYPE

Download         Length: 351 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References