Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 2651736..2652371 Replicon chromosome
Accession NZ_CP118270
Organism Paenibacillus marchantiae strain BMpBG1

Toxin (Protein)


Gene name mazF Uniprot ID W4B4V0
Locus tag PTQ21_RS11935 Protein ID WP_024630714.1
Coordinates 2652021..2652371 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag PTQ21_RS11930 Protein ID WP_274569993.1
Coordinates 2651736..2652017 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTQ21_RS11915 (PTQ21_11915) 2646836..2648329 - 1494 WP_274569991.1 serine hydrolase -
PTQ21_RS11920 (PTQ21_11920) 2648625..2649827 + 1203 WP_274569992.1 outer membrane lipoprotein-sorting protein -
PTQ21_RS11925 (PTQ21_11925) 2650287..2651474 + 1188 WP_064640023.1 alanine racemase -
PTQ21_RS11930 (PTQ21_11930) 2651736..2652017 + 282 WP_274569993.1 ribbon-helix-helix protein, CopG family Antitoxin
PTQ21_RS11935 (PTQ21_11935) 2652021..2652371 + 351 WP_024630714.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PTQ21_RS11940 (PTQ21_11940) 2652606..2654795 + 2190 WP_274569994.1 alpha-galactosidase -
PTQ21_RS11945 (PTQ21_11945) 2655070..2657292 + 2223 WP_063564442.1 Tex family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12778.77 Da        Isoelectric Point: 5.1184

>T272976 WP_024630714.1 NZ_CP118270:2652021-2652371 [Paenibacillus marchantiae]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTCIVAAITAQIQKAKLPTHVEIDAAAHGFDRDSVILLEQI
RTIDKQRLTDKITHLDEETMKLVNEALQISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10795.39 Da        Isoelectric Point: 5.1767

>AT272976 WP_274569993.1 NZ_CP118270:2651736-2652017 [Paenibacillus marchantiae]
VANLQNTKRIMISLPDYLLQEVDGIVALENSNRSELIRQAMKLYLTERKKRYIRESMQRGYMEMAKINLTMASEAFHAEE
DADSTLDRLVSEV

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W4B4V0

Antitoxin

Source ID Structure

References