Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3451213..3451916 Replicon chromosome
Accession NZ_CP118269
Organism Pantoea sp. Lij88

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag PU624_RS20035 Protein ID WP_283546362.1
Coordinates 3451213..3451554 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag PU624_RS20040 Protein ID WP_283546363.1
Coordinates 3451575..3451916 (-) Length 114 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PU624_RS20020 (PU624_20020) 3446569..3446830 - 262 Protein_3150 hypothetical protein -
PU624_RS20025 (PU624_20025) 3446999..3447946 - 948 WP_283546360.1 hypothetical protein -
PU624_RS20030 (PU624_20030) 3448988..3451021 + 2034 WP_283546361.1 hypothetical protein -
PU624_RS20035 (PU624_20035) 3451213..3451554 - 342 WP_283546362.1 TA system toxin CbtA family protein Toxin
PU624_RS20040 (PU624_20040) 3451575..3451916 - 342 WP_283546363.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PU624_RS20045 (PU624_20045) 3451927..3452160 - 234 Protein_3155 JAB domain-containing protein -
PU624_RS20050 (PU624_20050) 3452866..3454602 + 1737 WP_283546364.1 hypothetical protein -
PU624_RS20055 (PU624_20055) 3455219..3456277 + 1059 WP_283546365.1 DNA cytosine methyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3446999..3471019 24020


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-112)

Antitoxin

(13-112)


Sequences


Toxin        


Download         Length: 114 a.a.        Molecular weight: 12834.92 Da        Isoelectric Point: 10.3456

>T272974 WP_283546362.1 NZ_CP118269:c3451554-3451213 [Pantoea sp. Lij88]
MKTLPATTQRAAKLCLSSVAVWQMLLARLLEQHYGLILNDTPFSNEAVIQEHINAGINLAGAVNFLVEKYELVRIDRRGF
NWQEQSPYLRAVDILRARQATGLLRRSCKNAVR

Download         Length: 342 bp


Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12760.34 Da        Isoelectric Point: 5.5424

>AT272974 WP_283546363.1 NZ_CP118269:c3451916-3451575 [Pantoea sp. Lij88]
MKSTESENNSFLKWGLNRNVTPCFGDRLVQEGNRLHYLADRASITGEFSNAESLKLDEVLPCFISQMESMLTTGEMNPRH
AHCVTLYHNGFTCEADTLGSCGYLYISVYPTQR

Download         Length: 342 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References