Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-HipB |
Location | 2053756..2055317 | Replicon | chromosome |
Accession | NZ_CP118269 | ||
Organism | Pantoea sp. Lij88 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | - |
Locus tag | PU624_RS13330 | Protein ID | WP_283545369.1 |
Coordinates | 2054004..2055317 (+) | Length | 438 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | - |
Locus tag | PU624_RS13325 | Protein ID | WP_283545368.1 |
Coordinates | 2053756..2054004 (+) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PU624_RS13305 (PU624_13305) | 2049142..2051367 | + | 2226 | WP_283545365.1 | iron ABC transporter permease | - |
PU624_RS13310 (PU624_13310) | 2051364..2052425 | + | 1062 | WP_283545366.1 | ABC transporter ATP-binding protein | - |
PU624_RS13315 (PU624_13315) | 2052449..2053240 | + | 792 | WP_283545367.1 | inositol monophosphatase family protein | - |
PU624_RS13320 (PU624_13320) | 2053270..2053579 | - | 310 | Protein_1842 | N-acetyltransferase | - |
PU624_RS13325 (PU624_13325) | 2053756..2054004 | + | 249 | WP_283545368.1 | type II toxin-antitoxin system antitoxin HipB | Antitoxin |
PU624_RS13330 (PU624_13330) | 2054004..2055317 | + | 1314 | WP_283545369.1 | type II toxin-antitoxin system HipA family toxin | Toxin |
PU624_RS13335 (PU624_13335) | 2055412..2055618 | + | 207 | WP_283545370.1 | type II toxin-antitoxin system MqsA family antitoxin | - |
PU624_RS13340 (PU624_13340) | 2055906..2057279 | + | 1374 | WP_283545371.1 | M24 family metallopeptidase | - |
PU624_RS13345 (PU624_13345) | 2057394..2059439 | + | 2046 | WP_283545372.1 | FUSC family protein | - |
PU624_RS13350 (PU624_13350) | 2059777..2060118 | - | 342 | WP_283545373.1 | gamma-glutamylcyclotransferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 438 a.a. Molecular weight: 49057.68 Da Isoelectric Point: 8.8536
>T272971 WP_283545369.1 NZ_CP118269:2054004-2055317 [Pantoea sp. Lij88]
MKRLVAWMNGERVGVLTRQRNGAHEFQYDTGWLSNPLSRPLSLSMPLQVKAITSHAVINFFDNLLPDSPLIRDRIVARYQ
IKSRQPFDLLQEVGRDSVGATMLLPPDMPLPALQARFEVLDEARLESVLSAYQSDIPLGMLREETDFRISVAGAQEKTAL
LLTEEGWSIPAGATPTSHIIKLPIGEIKQPAATLDMRESVENEYLCLALARALGIDVPQATIIRAGKMRALAVERFDRRW
SRDKSRLIRLPQEDFCQALGLPSSTKYESDGGPGIAEIMQILMGSSKAIEDRYRFMLFQVFQWLIGATDGHAKNFSLFIE
RGGSYRLTPFYDVISAYPVLGGTGLNKRALKLAMGLRATKGKKTEIDKIFPRHFIATAKQVSFDRDSLQQIFDFFINAFP
QAVVSVRDALPADFPQHIADAIFSHSLIMLERLRHTE
MKRLVAWMNGERVGVLTRQRNGAHEFQYDTGWLSNPLSRPLSLSMPLQVKAITSHAVINFFDNLLPDSPLIRDRIVARYQ
IKSRQPFDLLQEVGRDSVGATMLLPPDMPLPALQARFEVLDEARLESVLSAYQSDIPLGMLREETDFRISVAGAQEKTAL
LLTEEGWSIPAGATPTSHIIKLPIGEIKQPAATLDMRESVENEYLCLALARALGIDVPQATIIRAGKMRALAVERFDRRW
SRDKSRLIRLPQEDFCQALGLPSSTKYESDGGPGIAEIMQILMGSSKAIEDRYRFMLFQVFQWLIGATDGHAKNFSLFIE
RGGSYRLTPFYDVISAYPVLGGTGLNKRALKLAMGLRATKGKKTEIDKIFPRHFIATAKQVSFDRDSLQQIFDFFINAFP
QAVVSVRDALPADFPQHIADAIFSHSLIMLERLRHTE
Download Length: 1314 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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