Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 1385230..1385873 Replicon chromosome
Accession NZ_CP118269
Organism Pantoea sp. Lij88

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag PU624_RS10240 Protein ID WP_283547520.1
Coordinates 1385230..1385646 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag PU624_RS10245 Protein ID WP_283547521.1
Coordinates 1385643..1385873 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PU624_RS10215 (PU624_10215) 1381147..1381722 - 576 WP_090959377.1 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase -
PU624_RS10220 (PU624_10220) 1382235..1382942 - 708 WP_283547517.1 phosphatase PAP2 family protein -
PU624_RS10225 (PU624_10225) 1382988..1383956 - 969 WP_283547518.1 GTP-binding protein -
PU624_RS10230 (PU624_10230) 1384032..1384604 - 573 WP_003854146.1 elongation factor P-like protein YeiP -
PU624_RS10235 (PU624_10235) 1384936..1385190 + 255 WP_283547519.1 YkgJ family cysteine cluster protein -
PU624_RS10240 (PU624_10240) 1385230..1385646 - 417 WP_283547520.1 type II toxin-antitoxin system VapC family toxin Toxin
PU624_RS10245 (PU624_10245) 1385643..1385873 - 231 WP_283547521.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PU624_RS10250 (PU624_10250) 1386378..1387508 + 1131 WP_283547522.1 fused PTS fructose transporter subunit IIA/HPr protein -
PU624_RS10255 (PU624_10255) 1387505..1388443 + 939 WP_090959394.1 1-phosphofructokinase -
PU624_RS10260 (PU624_10260) 1388460..1390172 + 1713 WP_283547523.1 PTS fructose transporter subunit IIBC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-129)

Antitoxin

SpoVT-AbrB domain

(7-48)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15280.63 Da        Isoelectric Point: 8.5382

>T272969 WP_283547520.1 NZ_CP118269:c1385646-1385230 [Pantoea sp. Lij88]
VNKTYMLDTNICSFIMREQPEEVIRRLEQAVLRNHRIVVSAITYAEMRFGAIGKKASPRHMHLVDAFCARLDAVLSWDRA
AVDATTEIKAALAAAGTPIGPNDTAIAGHAIAARAILVTNNTREFQRVPGLQLEDWVR

Download         Length: 417 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8933.07 Da        Isoelectric Point: 4.4992

>AT272969 WP_283547521.1 NZ_CP118269:c1385873-1385643 [Pantoea sp. Lij88]
MRIVSVFRNGNNRAIRLPRDMDFEGVSELEIIREGDAIILRPVRPTWRSFTQFEKADADFMTEREDVVSDEGRFDL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References