272967

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FaRel2-ATfaRel2/-
Location 60235..61030 Replicon plasmid pQHY-2
Accession NZ_CP118266
Organism Clostridium perfringens strain QHY-2

Toxin (Protein)


Gene name faRel2 Uniprot ID -
Locus tag PVA22_RS15830 Protein ID WP_173706021.1
Coordinates 60235..60825 (+) Length 197 a.a.

Antitoxin (Protein)


Gene name ATfaRel2 Uniprot ID B1BRB4
Locus tag PVA22_RS15835 Protein ID WP_004456691.1
Coordinates 60806..61030 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVA22_RS15775 (PVA22_15775) 55477..55689 + 213 WP_173706015.1 hypothetical protein -
PVA22_RS15780 (PVA22_15780) 55676..56635 + 960 WP_173706016.1 hypothetical protein -
PVA22_RS15785 (PVA22_15785) 56645..56917 + 273 WP_173706017.1 hypothetical protein -
PVA22_RS15790 (PVA22_15790) 57033..57293 + 261 WP_004456627.1 hypothetical protein -
PVA22_RS15795 (PVA22_15795) 57586..57939 + 354 WP_173706018.1 hypothetical protein -
PVA22_RS15800 (PVA22_15800) 57956..58345 + 390 WP_173706019.1 hypothetical protein -
PVA22_RS15805 (PVA22_15805) 58362..58682 + 321 WP_004456606.1 hypothetical protein -
PVA22_RS15810 (PVA22_15810) 58686..59072 + 387 WP_004456489.1 hypothetical protein -
PVA22_RS15815 (PVA22_15815) 59092..59514 + 423 WP_004456648.1 hypothetical protein -
PVA22_RS15820 (PVA22_15820) 59628..59858 + 231 WP_173706020.1 hypothetical protein -
PVA22_RS15825 (PVA22_15825) 59904..60215 + 312 WP_004456613.1 hypothetical protein -
PVA22_RS15830 (PVA22_15830) 60235..60825 + 591 WP_173706021.1 hypothetical protein Toxin
PVA22_RS15835 (PVA22_15835) 60806..61030 + 225 WP_004456691.1 hypothetical protein Antitoxin
PVA22_RS15840 (PVA22_15840) 61061..62011 - 951 WP_221366827.1 hypothetical protein -
PVA22_RS15845 (PVA22_15845) 62382..62912 + 531 WP_173706024.1 hypothetical protein -
PVA22_RS15850 (PVA22_15850) 63074..63301 + 228 WP_221366826.1 hypothetical protein -
PVA22_RS15855 (PVA22_15855) 63380..64504 + 1125 WP_173706026.1 nuclease-related domain-containing protein -
PVA22_RS15860 (PVA22_15860) 64637..64924 + 288 WP_043013024.1 hypothetical protein -
PVA22_RS15865 (PVA22_15865) 65048..65335 + 288 WP_004456644.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid erm(Q) / erm(B) / aac(6')-aph(2'') / fexA / optrA / erm(A) - 1..166452 166452


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(57-159)

Antitoxin

Protein of unknown function DUF6718

(1-72)


Sequences

Toxin        


Download         Length: 197 a.a.        Molecular weight: 23493.87 Da        Isoelectric Point: 9.2173

>T272967 WP_173706021.1 NZ_CP118266:60235-60825 [Clostridium perfringens]
MIDISILDKLSYKSNLNKSLKNTLRKFNKEDIMTELLDIRGFYEKNQLLTTIKFDYRIKSFQSSLLKYDKYFPSTELKKC
FNDLLGFRIVIDNYNELDNISLENFRIADMRNGKANDDGYRGIHLYYQKSNRHYPIELQINTVKDRIFNDWLHQELYKYV
SNNNIGIELRKKYDDGIITSLEDFKGELKKHVLYNI

Download         Length: 591 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8547.92 Da        Isoelectric Point: 5.0178

>AT272967 WP_004456691.1 NZ_CP118266:60806-61030 [Clostridium perfringens]
MCYIISKKFNELGCYALKSELGDKLASLSRYLTLATLDKNVQIVTISDPNVYKEYEPYTFVISEKEFINKTLEL

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References