272953

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4603578..4604397 Replicon chromosome
Accession NZ_CP118223
Organism Klebsiella grimontii strain YWC001

Toxin (Protein)


Gene name yjhX Uniprot ID A0A9E1D5M6
Locus tag PVK07_RS21675 Protein ID WP_004132607.1
Coordinates 4604140..4604397 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID A0A9E1DGJ5
Locus tag PVK07_RS21670 Protein ID WP_004132606.1
Coordinates 4603578..4604129 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVK07_RS21650 (PVK07_21650) 4598967..4600364 + 1398 WP_004132593.1 MFS transporter -
PVK07_RS21655 (PVK07_21655) 4600488..4601828 + 1341 WP_049085654.1 carbohydrate porin -
PVK07_RS21660 (PVK07_21660) 4601932..4602678 - 747 WP_224238150.1 class I SAM-dependent methyltransferase -
PVK07_RS21665 (PVK07_21665) 4603105..4603464 - 360 Protein_4261 class I SAM-dependent methyltransferase -
PVK07_RS21670 (PVK07_21670) 4603578..4604129 - 552 WP_004132606.1 N-acetyltransferase Antitoxin
PVK07_RS21675 (PVK07_21675) 4604140..4604397 - 258 WP_004132607.1 YjhX family toxin Toxin
PVK07_RS21680 (PVK07_21680) 4604981..4606165 + 1185 WP_049085652.1 mannonate dehydratase -
PVK07_RS21685 (PVK07_21685) 4606242..4607717 + 1476 WP_148865109.1 fructuronate reductase -
PVK07_RS21690 (PVK07_21690) 4607854..4608630 + 777 WP_116944170.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(34-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9538.04 Da        Isoelectric Point: 11.1381

>T272953 WP_004132607.1 NZ_CP118223:c4604397-4604140 [Klebsiella grimontii]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19990.89 Da        Isoelectric Point: 7.2343

>AT272953 WP_004132606.1 NZ_CP118223:c4604129-4603578 [Klebsiella grimontii]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References