Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2053593..2053761 Replicon chromosome
Accession NZ_CP118223
Organism Klebsiella grimontii strain YWC001

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2053651..2053754 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2053593..2053761 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVK07_RS09740 (PVK07_09740) 2048720..2050780 + 2061 WP_116943571.1 oligopeptidase B -
PVK07_RS09745 (PVK07_09745) 2050787..2051446 - 660 WP_004134816.1 exodeoxyribonuclease X -
PVK07_RS09750 (PVK07_09750) 2051525..2051755 - 231 WP_004103351.1 DNA polymerase III subunit theta -
PVK07_RS09755 (PVK07_09755) 2051891..2052265 + 375 WP_004134817.1 CopC domain-containing protein YobA -
PVK07_RS09760 (PVK07_09760) 2052270..2053139 + 870 WP_201160267.1 copper homeostasis membrane protein CopD -
PVK07_RS09765 (PVK07_09765) 2053156..2053494 + 339 WP_004103344.1 YebY family protein -
- 2053593..2053761 - 169 - - Antitoxin
- 2053651..2053754 + 104 - - Toxin
PVK07_RS09770 (PVK07_09770) 2053879..2054838 - 960 WP_049085573.1 spore coat protein U domain-containing protein -
PVK07_RS09775 (PVK07_09775) 2054853..2057183 - 2331 WP_049089570.1 fimbria/pilus outer membrane usher protein -
PVK07_RS09780 (PVK07_09780) 2057186..2057950 - 765 WP_004134823.1 fimbria/pilus periplasmic chaperone -
PVK07_RS09785 (PVK07_09785) 2057969..2058487 - 519 WP_049099811.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T272948 NZ_CP118223:2053651-2053754 [Klebsiella grimontii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT272948 NZ_CP118223:c2053761-2053593 [Klebsiella grimontii]
AATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References