Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 13254..13744 Replicon plasmid p28
Accession NZ_CP118183
Organism Entomospira culicis strain BR151

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PVA46_RS08290 Protein ID WP_167696526.1
Coordinates 13254..13523 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PVA46_RS08295 Protein ID WP_167696527.1
Coordinates 13523..13744 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVA46_RS08270 (PVA46_08270) 8848..10653 + 1806 WP_167696518.1 AAA family ATPase -
PVA46_RS08275 (PVA46_08275) 10793..11086 - 294 WP_167696520.1 hypothetical protein -
PVA46_RS08280 (PVA46_08280) 11076..11750 - 675 WP_167696522.1 ParA family protein -
PVA46_RS08285 (PVA46_08285) 11963..12889 + 927 WP_167696524.1 hypothetical protein -
PVA46_RS08290 (PVA46_08290) 13254..13523 - 270 WP_167696526.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PVA46_RS08295 (PVA46_08295) 13523..13744 - 222 WP_167696527.1 DUF6290 family protein Antitoxin
PVA46_RS08300 (PVA46_08300) 14276..15229 + 954 WP_167696529.1 tyrosine-type recombinase/integrase -
PVA46_RS08305 (PVA46_08305) 15349..16263 + 915 WP_167696531.1 Abi family protein -
PVA46_RS08310 (PVA46_08310) 16480..17448 + 969 WP_167696533.1 recombinase family protein -
PVA46_RS08315 (PVA46_08315) 17469..18027 - 559 Protein_17 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..28402 28402


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-86)

Antitoxin

Protein of unknown function DUF6290

(2-68)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10256.07 Da        Isoelectric Point: 10.1012

>T272940 WP_167696526.1 NZ_CP118183:c13523-13254 [Entomospira culicis]
MTYTLHYTTVAIKALKKLDRPSQILIMNWIEKHLIDCEDPRSKGKALKANLSGAWRYRIGDYRIIAEIDDSTVTILLLAI
GHRKAIYNK

Download         Length: 270 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8664.73 Da        Isoelectric Point: 4.6717

>AT272940 WP_167696527.1 NZ_CP118183:c13744-13523 [Entomospira culicis]
MTISIRFNDEEAELIKQYAKHKKTTVSQVMRESILAELEDEYDIDAYQQAMQAYKEHPITHNHDEVKKLLDLE

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References