Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1013211..1013984 Replicon chromosome
Accession NZ_CP118163
Organism Staphylococcus hyicus strain SG-7

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag PTA87_RS05035 Protein ID WP_167693803.1
Coordinates 1013829..1013984 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID A0A0A8HNH4
Locus tag PTA87_RS05030 Protein ID WP_039644857.1
Coordinates 1013211..1013810 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTA87_RS05010 1009521..1010243 + 723 WP_039644852.1 amino acid ABC transporter ATP-binding protein -
PTA87_RS05015 1010408..1011535 + 1128 WP_252547564.1 tRNA epoxyqueuosine(34) reductase QueG -
PTA87_RS05020 1011538..1012008 + 471 WP_039644854.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
PTA87_RS05025 1012024..1013193 + 1170 WP_274316401.1 N-acetylglucosamine-6-phosphate deacetylase -
PTA87_RS05030 1013211..1013810 + 600 WP_039644857.1 glucosamine-6-phosphate isomerase Antitoxin
PTA87_RS05035 1013829..1013984 + 156 WP_167693803.1 SAS053 family protein Toxin
PTA87_RS05040 1014140..1014544 + 405 WP_039644859.1 hypothetical protein -
PTA87_RS05045 1014702..1016087 + 1386 WP_274316402.1 class II fumarate hydratase -
PTA87_RS05050 1016109..1017635 + 1527 WP_274316403.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 5989.31 Da        Isoelectric Point: 3.9940

>T272915 WP_167693803.1 NZ_CP118163:1013829-1013984 [Staphylococcus hyicus]
MSEEKHIEHENEMVDNFDDLVQLGKEMEQISETNDQDKLNQSHDSEGRSNQ

Download         Length: 156 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22363.41 Da        Isoelectric Point: 6.0248

>AT272915 WP_039644857.1 NZ_CP118163:1013211-1013810 [Staphylococcus hyicus]
MAMNFKVFKDKDTAAIYAADIIRKQFNNNPTTIAGFHLNEEAAPVLDYLKRNVDDHAVDFSQIHILDYDKQTSYFKALGV
PEKQIHEIPEEDEVEKFIERKAKTKDNKGKLTLQVVSINNKGEFGIPVTNGLKPAREIFVVVTGSEKADVIKKLYEDNGN
TSFIPSSLKAHRMVNVILDEAAAQGLPDDVRAYFTSLYA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0A8HNH4

References