Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4225768..4226287 Replicon chromosome
Accession NZ_CP118156
Organism Pseudomonas chlororaphis strain ATCC 15926

Toxin (Protein)


Gene name relE Uniprot ID A0A1H3UB31
Locus tag PUP74_RS18975 Protein ID WP_007930524.1
Coordinates 4225768..4226049 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1H3UB71
Locus tag PUP74_RS18980 Protein ID WP_009044432.1
Coordinates 4226039..4226287 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP74_RS18955 (PUP74_18955) 4221089..4221670 - 582 WP_253364919.1 hypothetical protein -
PUP74_RS18960 (PUP74_18960) 4221981..4222253 + 273 WP_007927368.1 hypothetical protein -
PUP74_RS18965 (PUP74_18965) 4223392..4223874 + 483 WP_009044429.1 acyl-CoA thioesterase -
PUP74_RS18970 (PUP74_18970) 4223927..4225576 + 1650 WP_274300395.1 FMN-binding glutamate synthase family protein -
PUP74_RS18975 (PUP74_18975) 4225768..4226049 - 282 WP_007930524.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP74_RS18980 (PUP74_18980) 4226039..4226287 - 249 WP_009044432.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUP74_RS18985 (PUP74_18985) 4226384..4227172 - 789 WP_085534323.1 helix-turn-helix transcriptional regulator -
PUP74_RS18990 (PUP74_18990) 4227257..4228255 + 999 WP_114760888.1 bile acid:sodium symporter family protein -
PUP74_RS18995 (PUP74_18995) 4228579..4230345 + 1767 WP_274360187.1 hypothetical protein -
PUP74_RS19000 (PUP74_19000) 4230418..4230879 + 462 WP_009044436.1 YccF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10890.73 Da        Isoelectric Point: 10.6993

>T272911 WP_007930524.1 NZ_CP118156:c4226049-4225768 [Pseudomonas chlororaphis]
MTYELEFSEKAWKEWQKLGPTLKEQFKKKLQERLVNPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQARKR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8997.37 Da        Isoelectric Point: 4.4142

>AT272911 WP_009044432.1 NZ_CP118156:c4226287-4226039 [Pseudomonas chlororaphis]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERENDPTIKVSLD
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H3UB31

Antitoxin

Source ID Structure
AlphaFold DB A0A1H3UB71

References