272910

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 2838739..2840468 Replicon chromosome
Accession NZ_CP118156
Organism Pseudomonas chlororaphis strain ATCC 15926

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag PUP74_RS12885 Protein ID WP_274301005.1
Coordinates 2839824..2840468 (-) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag PUP74_RS12880 Protein ID WP_274301006.1
Coordinates 2838739..2839827 (-) Length 363 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP74_RS12855 (PUP74_12855) 2834337..2834747 + 411 WP_274301010.1 hypothetical protein -
PUP74_RS12860 (PUP74_12860) 2834870..2835886 + 1017 WP_274301009.1 PDDEXK nuclease domain-containing protein -
PUP74_RS12865 (PUP74_12865) 2835987..2836427 + 441 WP_062825471.1 carboxymuconolactone decarboxylase family protein -
PUP74_RS12870 (PUP74_12870) 2836430..2837317 + 888 WP_274301008.1 RNA polymerase sigma factor SigJ -
PUP74_RS12875 (PUP74_12875) 2837640..2838401 - 762 WP_274301007.1 HNH endonuclease -
PUP74_RS12880 (PUP74_12880) 2838739..2839827 - 1089 WP_274301006.1 macro domain-containing protein Antitoxin
PUP74_RS12885 (PUP74_12885) 2839824..2840468 - 645 WP_274301005.1 DUF4433 domain-containing protein Toxin
PUP74_RS12890 (PUP74_12890) 2840465..2841037 - 573 WP_274301004.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
PUP74_RS12895 (PUP74_12895) 2841222..2842142 - 921 WP_274301003.1 restriction endonuclease -
PUP74_RS12900 (PUP74_12900) 2842437..2844812 + 2376 WP_274301002.1 DEAD/DEAH box helicase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 24816.30 Da        Isoelectric Point: 7.0171

>T272910 WP_274301005.1 NZ_CP118156:c2840468-2839824 [Pseudomonas chlororaphis]
MNYSRLNPEKALIWRIVHRDNLPWILDNGLHCASSDVQAPQYVNIGNVDLISKRRSRHVPITPGGVLADYVPFYFTPFSV
MMKNIHSGWSVQQRSNDEIVILVSSLYRVEQLGLPFVFTNAHAYPDWTNYYSDLANLSQIDWSILQRRDFKRDPDDPRKM
ERYQAEALIHHHLPITGLLGIMCHTDAMKECIEQDVTDRGLALPVHARPGWYFQ

Download         Length: 645 bp

Antitoxin


Download         Length: 363 a.a.        Molecular weight: 40755.93 Da        Isoelectric Point: 6.8388

>AT272910 WP_274301006.1 NZ_CP118156:c2839827-2838739 [Pseudomonas chlororaphis]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFSENYRLYSAACKAGEVETGRMHVTAVNELDGPRWIVNFPTK
RHWRSPSQMAWVTEGLHDLRRFLIENQVKSVAVPPLGAGNGGLKWPEVREQIVTVLGDLDVDILVFEPSNQYLNVAKRSG
VEKLTPARALIAELVRRYWILGMECSLLEIQKLAWFLERAIEKLPATENPLNLKFVAHKYGPYANRLEHLLNNLDGSYLH
CNKRISDAGISDVIWFDEERKAFLQTYLKTEAKEYSQALEHTAKLIDGFESPFGMELLATVDWLLSQEGISPTVPAMRDA
LKNWDGGAGAAVRKSRLFDDQALDIALKRLTSSSFMPEMATC

Download         Length: 1089 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References