Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2533479..2534064 Replicon chromosome
Accession NZ_CP118156
Organism Pseudomonas chlororaphis strain ATCC 15926

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP74_RS11560 Protein ID WP_274301021.1
Coordinates 2533771..2534064 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A3G7H967
Locus tag PUP74_RS11555 Protein ID WP_062822914.1
Coordinates 2533479..2533769 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP74_RS11545 (PUP74_11545) 2530994..2532376 + 1383 WP_062822916.1 efflux transporter outer membrane subunit -
PUP74_RS11550 (PUP74_11550) 2532495..2533082 + 588 WP_007923530.1 hypothetical protein -
PUP74_RS11555 (PUP74_11555) 2533479..2533769 - 291 WP_062822914.1 putative addiction module antidote protein Antitoxin
PUP74_RS11560 (PUP74_11560) 2533771..2534064 - 294 WP_274301021.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP74_RS11565 (PUP74_11565) 2534300..2535694 - 1395 WP_274301022.1 VOC family protein -
PUP74_RS11570 (PUP74_11570) 2535959..2537083 + 1125 WP_274301023.1 diguanylate cyclase -
PUP74_RS11575 (PUP74_11575) 2537177..2538421 + 1245 WP_274301024.1 M20/M25/M40 family metallo-hydrolase -
PUP74_RS11580 (PUP74_11580) 2538653..2539048 + 396 WP_062822909.1 carboxymuconolactone decarboxylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(11-94)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10764.40 Da        Isoelectric Point: 10.4234

>T272909 WP_274301021.1 NZ_CP118156:c2534064-2533771 [Pseudomonas chlororaphis]
MDYEILQTTVFARWHTTLRDLRARIAIARRIERASAGNLGDVKNLGGGLSEMRVNTGAGYRLYFTVRGHTLIVLLLGGDK
STQPADICQARSLAKEF

Download         Length: 294 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10253.80 Da        Isoelectric Point: 8.0096

>AT272909 WP_062822914.1 NZ_CP118156:c2533769-2533479 [Pseudomonas chlororaphis]
MSDTLLPFDIATLLDSDQAISEYLSQVLADGDTDELIRALGHVARARGMTQIAKATGQGRASLYKAFAPGAKPRFDTVVK
VMRALGLQLCTTVSRG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7H967

References