Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1221961..1222499 Replicon chromosome
Accession NZ_CP118156
Organism Pseudomonas chlororaphis strain ATCC 15926

Toxin (Protein)


Gene name relE Uniprot ID A0A285H8D2
Locus tag PUP74_RS05400 Protein ID WP_009042149.1
Coordinates 1222221..1222499 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PUP74_RS05395 Protein ID WP_009042148.1
Coordinates 1221961..1222224 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP74_RS05380 (PUP74_05380) 1217952..1220225 - 2274 WP_085529818.1 TonB-dependent siderophore receptor -
PUP74_RS05385 (PUP74_05385) 1220431..1221111 + 681 WP_085529819.1 Fe2+-dependent dioxygenase -
PUP74_RS05390 (PUP74_05390) 1221115..1221900 + 786 WP_274301535.1 tetratricopeptide repeat protein -
PUP74_RS05395 (PUP74_05395) 1221961..1222224 + 264 WP_009042148.1 ribbon-helix-helix domain-containing protein Antitoxin
PUP74_RS05400 (PUP74_05400) 1222221..1222499 + 279 WP_009042149.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP74_RS05405 (PUP74_05405) 1222574..1223737 - 1164 WP_009042150.1 type III PLP-dependent enzyme -
PUP74_RS05410 (PUP74_05410) 1224291..1225448 - 1158 WP_274301534.1 ABC transporter ATP-binding protein -
PUP74_RS05415 (PUP74_05415) 1225445..1226098 - 654 WP_053259627.1 ABC transporter permease -
PUP74_RS05420 (PUP74_05420) 1226113..1227006 - 894 WP_274301533.1 glycine betaine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10853.45 Da        Isoelectric Point: 8.5409

>T272907 WP_009042149.1 NZ_CP118156:1222221-1222499 [Pseudomonas chlororaphis]
VRELKWTSKALSDLARLFEFLAPVNRSVAARTVQSLTQAPDTLLTNPRIGEQLEEFQPRDVRRLLVGPYEMRYEIQDATL
YILRVWHVREDR

Download         Length: 279 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9768.17 Da        Isoelectric Point: 5.6088

>AT272907 WP_009042148.1 NZ_CP118156:1221961-1222224 [Pseudomonas chlororaphis]
MTATKVLTAHVPLELADKVDQMASRLERSRGWIVKQALVAWVDQEEERSRLTHEALADVDAGRVIDHQAVQAWAESLMND
KPLPVPK

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285H8D2

Antitoxin

Source ID Structure

References