Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 540805..541475 Replicon chromosome
Accession NZ_CP118156
Organism Pseudomonas chlororaphis strain ATCC 15926

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP74_RS02420 Protein ID WP_123411912.1
Coordinates 540805..541233 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A2N8BIH3
Locus tag PUP74_RS02425 Protein ID WP_062823999.1
Coordinates 541230..541475 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP74_RS02405 (PUP74_02405) 535927..538185 + 2259 WP_274301721.1 TonB-dependent receptor -
PUP74_RS02410 (PUP74_02410) 538232..539557 + 1326 WP_009041689.1 LLM class flavin-dependent oxidoreductase -
PUP74_RS02415 (PUP74_02415) 539642..540679 + 1038 WP_053259262.1 L-glyceraldehyde 3-phosphate reductase -
PUP74_RS02420 (PUP74_02420) 540805..541233 - 429 WP_123411912.1 type II toxin-antitoxin system VapC family toxin Toxin
PUP74_RS02425 (PUP74_02425) 541230..541475 - 246 WP_062823999.1 hypothetical protein Antitoxin
PUP74_RS02430 (PUP74_02430) 541603..542442 - 840 WP_274301720.1 taurine dioxygenase -
PUP74_RS02435 (PUP74_02435) 542527..543366 - 840 WP_009041694.1 taurine ABC transporter permease TauC -
PUP74_RS02440 (PUP74_02440) 543363..544157 - 795 WP_085533376.1 taurine ABC transporter ATP-binding subunit -
PUP74_RS02445 (PUP74_02445) 544252..545229 - 978 WP_009041696.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15853.46 Da        Isoelectric Point: 5.4985

>T272905 WP_123411912.1 NZ_CP118156:c541233-540805 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDASVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGRRKQMLHASALAMFEEDFIERIVPFGT
QAALYYAHLISHRESLGRPISLVDAQIAAICRVHDAAIATRNAKDFSDTGLIVINPWLPLEV

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9129.35 Da        Isoelectric Point: 7.3226

>AT272905 WP_062823999.1 NZ_CP118156:c541475-541230 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALNRTTDSQGLASRIRARFAEAGGVKLELPERTEPARVVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N8BIH3

References