Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 424141..424657 Replicon chromosome
Accession NZ_CP118156
Organism Pseudomonas chlororaphis strain ATCC 15926

Toxin (Protein)


Gene name stbE Uniprot ID A0A285EY61
Locus tag PUP74_RS01890 Protein ID WP_009041601.1
Coordinates 424376..424657 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A285F0M2
Locus tag PUP74_RS01885 Protein ID WP_062824057.1
Coordinates 424141..424386 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP74_RS01860 (PUP74_01860) 419904..420899 + 996 WP_274301767.1 sulfotransferase family protein -
PUP74_RS01865 (PUP74_01865) 420865..421623 - 759 WP_097134106.1 slipin family protein -
PUP74_RS01870 (PUP74_01870) 421625..423010 - 1386 WP_274301766.1 nodulation protein NfeD -
PUP74_RS01875 (PUP74_01875) 423234..423695 + 462 WP_062824058.1 YbaK/EbsC family protein -
PUP74_RS01880 (PUP74_01880) 423833..424078 + 246 WP_009041599.1 DUF2789 domain-containing protein -
PUP74_RS01885 (PUP74_01885) 424141..424386 + 246 WP_062824057.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PUP74_RS01890 (PUP74_01890) 424376..424657 + 282 WP_009041601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP74_RS01895 (PUP74_01895) 424789..425217 + 429 WP_085533251.1 MarR family transcriptional regulator -
PUP74_RS01900 (PUP74_01900) 425214..427298 + 2085 WP_087092318.1 FUSC family protein -
PUP74_RS01905 (PUP74_01905) 427295..427504 + 210 WP_007932080.1 DUF1656 domain-containing protein -
PUP74_RS01910 (PUP74_01910) 427501..428397 + 897 WP_274301765.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10879.81 Da        Isoelectric Point: 10.5797

>T272903 WP_009041601.1 NZ_CP118156:424376-424657 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8822.17 Da        Isoelectric Point: 5.0216

>AT272903 WP_062824057.1 NZ_CP118156:424141-424386 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLSGAHGGPVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285EY61

Antitoxin

Source ID Structure
AlphaFold DB A0A285F0M2

References