Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 545403..546073 Replicon chromosome
Accession NZ_CP118155
Organism Pseudomonas chlororaphis strain ATCC 17411

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PUP78_RS02435 Protein ID WP_124323278.1
Coordinates 545403..545831 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A3G7DZE9
Locus tag PUP78_RS02440 Protein ID WP_009046453.1
Coordinates 545828..546073 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP78_RS02405 (PUP78_02405) 540602..541090 - 489 WP_124323274.1 DoxX family membrane protein -
PUP78_RS02410 (PUP78_02410) 541147..541887 - 741 WP_124323275.1 SDR family oxidoreductase -
PUP78_RS02415 (PUP78_02415) 542017..542907 + 891 WP_124323276.1 LysR family transcriptional regulator -
PUP78_RS02420 (PUP78_02420) 543032..543214 + 183 WP_009041685.1 type II toxin-antitoxin system HicA family toxin -
PUP78_RS02425 (PUP78_02425) 543244..543645 + 402 WP_025808441.1 type II toxin-antitoxin system HicB family antitoxin -
PUP78_RS02430 (PUP78_02430) 544236..545273 + 1038 WP_124323277.1 L-glyceraldehyde 3-phosphate reductase -
PUP78_RS02435 (PUP78_02435) 545403..545831 - 429 WP_124323278.1 type II toxin-antitoxin system VapC family toxin Toxin
PUP78_RS02440 (PUP78_02440) 545828..546073 - 246 WP_009046453.1 plasmid stabilization protein Antitoxin
PUP78_RS02445 (PUP78_02445) 546213..547052 - 840 WP_124323279.1 taurine dioxygenase -
PUP78_RS02450 (PUP78_02450) 547290..548129 - 840 WP_124323280.1 taurine ABC transporter permease TauC -
PUP78_RS02455 (PUP78_02455) 548126..548920 - 795 WP_023970012.1 taurine ABC transporter ATP-binding subunit -
PUP78_RS02460 (PUP78_02460) 549031..550008 - 978 WP_124323281.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15862.37 Da        Isoelectric Point: 5.4577

>T272897 WP_124323278.1 NZ_CP118155:c545831-545403 [Pseudomonas chlororaphis]
MIVLDTNVLSELMHPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASALAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEI

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9103.27 Da        Isoelectric Point: 6.2314

>AT272897 WP_009046453.1 NZ_CP118155:c546073-545828 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALSRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7DZE9

References