Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 4735685..4736274 Replicon chromosome
Accession NZ_CP118154
Organism Pseudomonas chlororaphis strain ATCC 17414

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PUP71_RS21650 Protein ID WP_007924097.1
Coordinates 4735685..4735984 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PUP71_RS21655 Protein ID WP_009045810.1
Coordinates 4735981..4736274 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP71_RS21620 (PUP71_21620) 4731164..4732051 - 888 WP_053262814.1 (2E,6E)-farnesyl diphosphate synthase -
PUP71_RS21625 (PUP71_21625) 4732048..4732290 - 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PUP71_RS21630 (PUP71_21630) 4732517..4733605 + 1089 WP_053262813.1 copper-containing nitrite reductase -
PUP71_RS21635 (PUP71_21635) 4733672..4733971 + 300 WP_007924100.1 helix-turn-helix transcriptional regulator -
PUP71_RS21640 (PUP71_21640) 4734029..4735039 + 1011 WP_173613368.1 NAD(P)-dependent alcohol dehydrogenase -
PUP71_RS21645 (PUP71_21645) 4735064..4735513 - 450 WP_053262811.1 DUF3828 domain-containing protein -
PUP71_RS21650 (PUP71_21650) 4735685..4735984 + 300 WP_007924097.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PUP71_RS21655 (PUP71_21655) 4735981..4736274 + 294 WP_009045810.1 putative addiction module antidote protein Antitoxin
PUP71_RS21660 (PUP71_21660) 4736390..4736776 - 387 WP_053262810.1 hypothetical protein -
PUP71_RS21665 (PUP71_21665) 4737584..4738111 - 528 WP_003228599.1 inorganic diphosphatase -
PUP71_RS21670 (PUP71_21670) 4738376..4739185 - 810 WP_053262809.1 zinc-dependent peptidase -
PUP71_RS21675 (PUP71_21675) 4739191..4739847 - 657 WP_007924093.1 DedA family protein -
PUP71_RS21680 (PUP71_21680) 4740101..4740559 - 459 WP_053262808.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(47-90)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11326.08 Da        Isoelectric Point: 10.6613

>T272895 WP_007924097.1 NZ_CP118154:4735685-4735984 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVSPVGEGVSELRIHYGPGYRVYFQQRGLQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT272895 WP_009045810.1 NZ_CP118154:4735981-4736274 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSEKGNPTLKTLLA
VMRALGLDMTARVHGAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References